iPTMnet Report P08637 FCGR3A

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P08637 / FCG3A_HUMAN
Protein Name	Low affinity immunoglobulin gamma Fc region receptor III-A precursor
Gene Name	Name: FCGR3A Synonyms:CD16A;
Organism	Homo sapiens (Human)

PRO ID	PR:P08637 DAG View
PRO Name	low affinity immunoglobulin gamma Fc region receptor III-A (human)
Definition	A low affinity immunoglobulin gamma Fc region receptor III-A that is encoded in the genome of human.
Short Label	hFCGR3A
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P08637 (FCGR3A) as Substrate

P08637

Condensed View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	N63	N-Glycosylation		score4	GlyGen UniProt	21768335, 22023369
	T163	Phosphorylation		score1	PhosphoSitePlus
	S167	Phosphorylation		score1	PhosphoSitePlus
	S169	Phosphorylation		score1	PhosphoSitePlus
	Y170	Phosphorylation		score1	PhosphoSitePlus
	N180	N-Glycosylation		score4	GlyGen UniProt	21768335, 22023369
	S236	Phosphorylation		score2	UniProt	23024279
	T237	Phosphorylation		score2	UniProt	23024279

P08637 (FCGR3A) as PTM Enzyme

Protein as Phosphorylation Enzyme

	Substrate	Site	Score	Source	PMID
	P06239-1 (LCK)	Y394	score2	HPRD	18578522, 8405050, 8258691, ...15144186, 8945479

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
N63	K63	Biomuta		DOID:1324 / lung cancer [ cosmic ]
N180	Y180	Biomuta		DOID:1324 / lung cancer [ cosmic ]
T237	R237	Biomuta		DOID:1324 / lung cancer [ cosmic ]
T237	A237	Biomuta		DOID:1324 / lung cancer [ cosmic ]