iPTMnet Report for P08574 (CYC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P08574 / CY1_HUMAN
Protein Name Cytochrome c1, heme protein, mitochondrial precursor
Gene Name Name: CYC1
Organism Homo sapiens (Human)

PRO ID PR:P08574
DAG View
PRO Name cytochrome c1, heme protein, mitochondrial (human)
Definition A cytochrome c1, heme protein, mitochondrial that is encoded in the genome of human.
Short Label hCYC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P08574 (CYC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K50 Ubiquitination PhosphoSitePlus
S103 Phosphorylation PhosphoSitePlus
R112 Methylation PhosphoSitePlus
C139 Methylation IEDB 31844290
K170 Ubiquitination PhosphoSitePlus
Y174 Phosphorylation PhosphoSitePlus
K177 Ubiquitination PhosphoSitePlus
Y179 Phosphorylation PhosphoSitePlus
S182 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y199 Phosphorylation PhosphoSitePlus
C219 S-Nitrosylation dbSNO 26338901
C271 Methylation IEDB 31844290
S278 Phosphorylation PhosphoSitePlus
K307 Acetylation PhosphoSitePlus
K310 Acetylation PhosphoSitePlus
K318 Acetylation PhosphoSitePlus
K318 Ubiquitination PhosphoSitePlus
K325 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S103 C103 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
C271 R271 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K310 R310 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]