iPTMnet Report for P08572 (COL4A2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P08572 / CO4A2_HUMAN
Protein Name Collagen alpha-2(IV) chain precursor
Gene Name Name: COL4A2
Organism Homo sapiens (Human)

PRO ID PR:P08572
DAG View
PRO Name collagen alpha-2(IV) chain (human)
Definition A collagen alpha-2(IV) chain that is encoded in the genome of human.
Short Label hCOL4A2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P08572 (COL4A2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S111 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
N138 N-Glycosylation GlyGen   UniProt 3198637
T265 O-Glycosylation GlyGen 30459171
Y306 Phosphorylation PhosphoSitePlus
S321 Phosphorylation PhosphoSitePlus
Y327 Phosphorylation PhosphoSitePlus
K453 Acetylation PhosphoSitePlus
K456 Acetylation PhosphoSitePlus
K1002 Acetylation PhosphoSitePlus
T1087 O-Glycosylation GlyGen 34846842
T1096 O-Glycosylation GlyGen 34846842
T1204 Phosphorylation PhosphoSitePlus
S1303 Phosphorylation PhosphoSitePlus
S1309 Phosphorylation PhosphoSitePlus
T1313 Phosphorylation PhosphoSitePlus
T1361 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T1403 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T1403 Phosphorylation HPRD   PhosphoSitePlus 20068231
S1446 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S1446 Phosphorylation PhosphoSitePlus
S1485 Phosphorylation PhosphoSitePlus
K1494 Acetylation PhosphoSitePlus
Y1586 Phosphorylation HPRD 20068231
S1683 Phosphorylation PhosphoSitePlus
S1687 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y327 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
K453 E453 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K456 N456 Biomuta DOID:363 / uterine cancer [ icgc ]
T1204 I1204 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1687 L1687 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]