iPTMnet Report for P08476 (INHBA)
Protein Information
| UniProt AC / UniProt ID | P08476 / INHBA_HUMAN |
| Protein Name | Inhibin beta A chain precursor |
| Gene Name | Name: INHBA |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P08476 |
| PRO Name | inhibin beta A chain (human) |
| Definition | An activin/inhibin beta A chain that is encoded in the genome of human. |
| Short Label | hINHBA |
| Category | organism-gene |
DAG ViewP08476 (INHBA) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S26 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| S30 | O-Glycosylation | score1 | GlyGen | 30459171, 25813380 | ||
| S50 | O-Glycosylation | score1 | GlyGen | 30379171, 29351928 | ||
| K94 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T188 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S226 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y404 | Phosphorylation | score1 | PhosphoSitePlus |
Proteoform PPIs
|
Protein 1 | Relation | Protein 2 | Source | PMID |
|---|---|---|---|---|---|
| PR:000036540 (hINHBA/iso:1/Clv:1) | Interaction | PR:000036608 (hINHA/iso:1/ClvNGlyco:2) | PRO | 17456790, 7890768 | |
| PR:000036608 (hINHA/iso:1/ClvNGlyco:2) | Interaction | PR:000036540 (hINHBA/iso:1/Clv:1) | PRO | 17456790, 8885240 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S30 | R30 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S30 | N30 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] | |
| S50 | Y50 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] | |
| Y404 | C404 | Biomuta | DOID:1612 / breast cancer [ cosmic ] |
