iPTMnet Report for P08397 (HMBS)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P08397 / HEM3_HUMAN
Protein Name Porphobilinogen deaminase
Gene Name Name: HMBS
Synonyms:PBGD,UPS;
Organism Homo sapiens (Human)

PRO ID PR:P08397
DAG View
PRO Name porphobilinogen deaminase (human)
Definition A porphobilinogen deaminase that is encoded in the genome of human.
Short Label hHMBS
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P08397 (HMBS) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330, 22814378, 22223895
S2 Phosphorylation PhosphoSitePlus
S15 Phosphorylation PhosphoSitePlus   UniProt 23186163
K17 Acetylation PhosphoSitePlus
S69 Phosphorylation PhosphoSitePlus   UniProt 23186163
K70 Ubiquitination PhosphoSitePlus
K74 Acetylation PhosphoSitePlus
K74 Ubiquitination PhosphoSitePlus
K79 Ubiquitination PhosphoSitePlus
K87 Acetylation PhosphoSitePlus
C114 S-Nitrosylation dbSNO 19483679
K115 Ubiquitination PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus
K140 Ubiquitination PhosphoSitePlus
S147 Phosphorylation PhosphoSitePlus   UniProt 23186163
K157 Acetylation PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus
K176 Acetylation PhosphoSitePlus
K227 Ubiquitination PhosphoSitePlus
C261 S-Nitrosylation dbSNO 2212679, 22126794, 26338901
S262 Phosphorylation PhosphoSitePlus
T269 Phosphorylation PhosphoSitePlus
K345 Ubiquitination PhosphoSitePlus
K348 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S15 Phosphorylation HPRD 19413330