iPTMnet Report for P08240 (SRPRA)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P08240 / SRPRA_HUMAN
Protein Name Signal recognition particle receptor subunit alpha
Gene Name Name: SRPRA
Synonyms:SRPR;
Organism Homo sapiens (Human)

PRO ID PR:P08240
DAG View
PRO Name signal recognition particle receptor subunit alpha (human)
Definition A signal recognition particle receptor subunit alpha that is encoded in the genome of human.
Short Label hSRPRA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P08240 (SRPRA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T6 Phosphorylation PhosphoSitePlus
R41 Methylation PhosphoSitePlus
N44 N-Glycosylation GlyGen 24190977
T96 O-Glycosylation GlyGen 33465208
S102 O-Glycosylation GlyGen 33214551, 28411811, 34725712, ...33465208, 30620550
S105 O-Glycosylation GlyGen 33465208
S142 Phosphorylation PhosphoSitePlus
S151 Phosphorylation PhosphoSitePlus
T155 Phosphorylation PhosphoSitePlus
K163 Acetylation PhosphoSitePlus
K169 Acetylation PhosphoSitePlus
K170 Acetylation PhosphoSitePlus
S177 Phosphorylation PhosphoSitePlus   UniProt 23186163
K220 Ubiquitination PhosphoSitePlus
K242 Methylation PhosphoSitePlus
Y261 Phosphorylation phospho.ELM   PhosphoSitePlus 15592455
S262 Phosphorylation PhosphoSitePlus
T263 Phosphorylation PhosphoSitePlus
T266 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T269 Phosphorylation PhosphoSitePlus
T284 Phosphorylation PhosphoSitePlus   UniProt 24275569
S286 Phosphorylation PhosphoSitePlus
S296 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
S297 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
S298 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
S307 Phosphorylation phospho.ELM 18669648
S311 Phosphorylation PhosphoSitePlus
T313 Phosphorylation PhosphoSitePlus
T316 Phosphorylation PhosphoSitePlus
K331 Ubiquitination PhosphoSitePlus
S332 Phosphorylation PhosphoSitePlus
S334 Phosphorylation PhosphoSitePlus
K344 Ubiquitination PhosphoSitePlus
K369 Ubiquitination PhosphoSitePlus
K373 Ubiquitination PhosphoSitePlus
T377 O-Glycosylation GlyGen 33214551, 28411811, 34725712, ...33465208, 30620550
T382 Phosphorylation PhosphoSitePlus
S383 Phosphorylation PhosphoSitePlus
T384 Phosphorylation PhosphoSitePlus
T469 Phosphorylation PhosphoSitePlus
S473 Phosphorylation PhosphoSitePlus   UniProt 23186163
K492 Ubiquitination PhosphoSitePlus
K496 Ubiquitination PhosphoSitePlus
S574 Phosphorylation PhosphoSitePlus
T578 Phosphorylation PhosphoSitePlus   UniProt 23186163
K589 Ubiquitination PhosphoSitePlus
Y605 Phosphorylation PhosphoSitePlus
T607 Phosphorylation PhosphoSitePlus
S608 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y261 Phosphorylation HPRD 15592455
T266 Phosphorylation HPRD 18669648
T284 Phosphorylation HPRD 18691976, 17081983, 20068231
S286 Phosphorylation HPRD 18691976, 17081983
S296 Phosphorylation HPRD 17081983, 18452278, 18669648, ...20166139, 19415658, 20068231
S297 Phosphorylation HPRD 17081983, 18452278, 18669648, ...20166139, 19415658, 20068231
S298 Phosphorylation HPRD 17081983, 18452278, 18669648, ...20166139, 19415658, 20068231
S307 Phosphorylation HPRD 18669648
S311 Phosphorylation HPRD 18691976


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S151 Y151 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K170 R170 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ]
S177 Y177 Biomuta DOID:1324 / lung cancer [ cosmic ]
K242 E242 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T263 I263 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T263 A263 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T284 N284 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T284 A284 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S298 P298 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K331 N331 Biomuta DOID:1324 / lung cancer [ cosmic ]
T469 A469 Biomuta DOID:1324 / lung cancer [ cosmic ]
K492 N492 Biomuta DOID:1612 / breast cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic ]
K492 R492 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K496 N496 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
Y605 H605 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]