iPTMnet Report P08236 GUSB

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P08236 / BGLR_HUMAN
Protein Name	Beta-glucuronidase precursor
Gene Name	Name: GUSB
Organism	Homo sapiens (Human)

PRO ID	PR:P08236 DAG View
PRO Name	beta-glucuronidase (human)
Definition	A beta-glucuronidase that is encoded in the genome of human.
Short Label	hGUSB
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P08236 (GUSB) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	K39	Ubiquitination		score1	PhosphoSitePlus
	N173	N-Glycosylation		score2	GlyGen UniProt	34089345, 29741879, 19159218, ...24190977
	N174	N-Glycosylation		score1	GlyGen	24190977
	K251	Ubiquitination		score1	PhosphoSitePlus
	N272	N-Glycosylation		score2	GlyGen UniProt	16335952, 34089345, 19159218, ...24190977, 23090970, 29741879, 12754519
	T274	O-Glycosylation		score1	GlyGen	30444036, 30059200, 22661428, ...35254053
	T274	Phosphorylation		score2	phospho.ELM	8505339
	T276	O-Glycosylation		score1	GlyGen	22661428
	K359	Ubiquitination		score1	PhosphoSitePlus
	K368	Ubiquitination		score1	PhosphoSitePlus
	K576	Ubiquitination		score1	PhosphoSitePlus
	N631	N-Glycosylation		score2	GlyGen UniProt	29741879, 19159218, 24190977
	K641	Ubiquitination		score1	PhosphoSitePlus
	C644	S-Nitrosylation		score0	dbSNO	26338901

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	N173	N-Glycosylation		score1	PRO	29741879
	T274	Phosphorylation		score1	HPRD	8505339

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
N631	T631	Biomuta		DOID:3571 / liver cancer [ cosmic ]