Protein Information

Cytoscape View


UniProt AC / UniProt ID P08195 / 4F2_HUMAN
Protein Name 4F2 cell-surface antigen heavy chain
Gene Name Name: SLC3A2
Synonyms:MDU1;
Organism Homo sapiens (Human)

PRO ID PR:P08195
DAG View
PRO Name 4F2 cell-surface antigen heavy chain (human)
Definition A 4F2 cell-surface antigen heavy chain that is encoded in the genome of human.
Short Label hSLC3A2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P08195 (SLC3A2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
S9 Phosphorylation HPRD   PhosphoSitePlus 18491316, 20068231
S41 Phosphorylation HPRD 18669648
S103 Phosphorylation PhosphoSitePlus   UniProt 23186163
T106 Phosphorylation PhosphoSitePlus
K111 Ubiquitination PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
S129 Phosphorylation PhosphoSitePlus
S134 Phosphorylation PhosphoSitePlus   UniProt 23186163
K140 Ubiquitination PhosphoSitePlus
K145 Ubiquitination PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
K160 Ubiquitination PhosphoSitePlus
T162 Phosphorylation PhosphoSitePlus
S165 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
K166 Acetylation PhosphoSitePlus
K166 Sumoylation PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
S175 Phosphorylation PhosphoSitePlus
T181 Phosphorylation PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
K245 Ubiquitination PhosphoSitePlus
Y250 Phosphorylation PhosphoSitePlus
K255 Ubiquitination PhosphoSitePlus
K257 Ubiquitination PhosphoSitePlus
K266 Ubiquitination PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
K287 Ubiquitination PhosphoSitePlus
S292 Phosphorylation PhosphoSitePlus
S296 Phosphorylation PhosphoSitePlus
K298 Ubiquitination PhosphoSitePlus
S301 Phosphorylation PhosphoSitePlus
T309 Phosphorylation PhosphoSitePlus
Y312 Phosphorylation PhosphoSitePlus
S317 Phosphorylation PhosphoSitePlus
S320 Phosphorylation PhosphoSitePlus
T321 Phosphorylation PhosphoSitePlus
K329 Ubiquitination PhosphoSitePlus
K354 Ubiquitination PhosphoSitePlus
N365 N-Glycosylation UniProt 12754519, 19159218, 19349973
K368 Ubiquitination PhosphoSitePlus
N381 N-Glycosylation UniProt 16335952, 12754519, 19159218, ...19349973
S402 Phosphorylation PhosphoSitePlus
S403 Phosphorylation PhosphoSitePlus
Y404 Phosphorylation PhosphoSitePlus
S406 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   UniProt 19065266
S408 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   UniProt 19065266
S410 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   UniProt 19065266
K416 Ubiquitination PhosphoSitePlus
N424 N-Glycosylation UniProt 16335952, 12754519, 19139490, ...19349973
T442 Phosphorylation PhosphoSitePlus
S443 Phosphorylation PhosphoSitePlus
N506 N-Glycosylation UniProt 19159218, 19349973
S513 Phosphorylation PhosphoSitePlus
S518 Phosphorylation PhosphoSitePlus
S521 Phosphorylation PhosphoSitePlus
S527 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   UniProt 19065266
S531 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   UniProt 19065266
S598 Phosphorylation PhosphoSitePlus
S607 Phosphorylation PhosphoSitePlus
K615 Ubiquitination PhosphoSitePlus
R625 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S9 Phosphorylation HPRD 18491316, 20068231
S103 Phosphorylation HPRD 19651622, 17081983, 20068231, ...19691289
T106 Phosphorylation HPRD 17081983
S134 Phosphorylation HPRD 17081983
S301 Phosphorylation HPRD 18452278
Y312 Phosphorylation HPRD 18452278
S607 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation HPRD 19651622, 17081983, 20068231, ...19691289
T5 Phosphorylation HPRD 17081983
S33 Phosphorylation HPRD 17081983
S200 Phosphorylation HPRD 18452278
Y211 Phosphorylation HPRD 18452278
S506 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S9 Phosphorylation HPRD 18491316, 20068231
S41 Phosphorylation HPRD 19651622, 17081983, 20068231, ...19691289
T44 Phosphorylation HPRD 17081983
K49 Ubiquitination PhosphoSitePlus
S72 Phosphorylation HPRD 17081983
S239 Phosphorylation HPRD 18452278
Y250 Phosphorylation HPRD 18452278
S545 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K140 N140 Biomuta DOID:363 / uterine cancer [ tcga ]
K145 N145 Biomuta DOID:1793 / pancreatic cancer [ tcga ]
K160 T160 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
K287 N287 Biomuta DOID:3571 / liver cancer [ icgc ]
S301 I301 Biomuta DOID:1324 / lung cancer [ tcga ]
S320 P320 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
K329 M329 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
K354 E354 Biomuta DOID:363 / uterine cancer [ tcga ]
S403 * Biomuta DOID:1790 / malignant mesothelioma [ tcga ]
S408 F408 Biomuta DOID:1324 / lung cancer [ tcga ]
N506 S506 Biomuta DOID:3070 / malignant glioma [ tcga ]
S518 F518 Biomuta DOID:1909 / melanoma [ tcga ]
S607 F607 Biomuta DOID:8618 / oral cavity cancer [ icgc ] DOID:1324 / lung cancer [ cosmic, tcga ]