iPTMnet Report for P08174 (CD55)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P08174 / DAF_HUMAN
Protein Name Complement decay-accelerating factor precursor
Gene Name Name: CD55
Synonyms:CR,DAF;
Organism Homo sapiens (Human)

PRO ID PR:P08174
DAG View
PRO Name complement decay-accelerating factor (human)
Definition A complement decay-accelerating factor that is encoded in the genome of human.
Short Label hCD55
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P08174 (CD55) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K64 Ubiquitination PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
K76 Ubiquitination PhosphoSitePlus
N95 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...24190977
K110 Ubiquitination PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
S162 Phosphorylation PhosphoSitePlus
Y245 Phosphorylation PhosphoSitePlus
Y251 Phosphorylation PhosphoSitePlus
Y266 Phosphorylation PhosphoSitePlus
K291 Ubiquitination PhosphoSitePlus
T295 O-Glycosylation GlyGen 31373491
K298 Ubiquitination PhosphoSitePlus
T306 O-Glycosylation GlyGen 25813380, 31373491
T307 O-Glycosylation GlyGen 25813380
S310 O-Glycosylation GlyGen 31373491
S310 Phosphorylation PhosphoSitePlus
K315 Ubiquitination PhosphoSitePlus
K319 Ubiquitination PhosphoSitePlus
S334 Phosphorylation PhosphoSitePlus
K338 Ubiquitination PhosphoSitePlus
T343 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T344 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
K347 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S140 Phosphorylation HPRD 20068231, 17924679
Site PTM Type PTM Enzyme Score Source PMID
S360 Phosphorylation PhosphoSitePlus
T366 Phosphorylation PhosphoSitePlus
Y430 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S415 Phosphorylation PhosphoSitePlus
S478 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K64 N64 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
K64 R64 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K64 T64 Biomuta DOID:363 / uterine cancer [ icgc ]
N95 K95 Biomuta [ cosmic ]
S162 L162 Biomuta DOID:4159 / skin cancer [ cosmic ]
T306 A306 Biomuta DOID:3571 / liver cancer [ cosmic ]
S310 L310 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S334 F334 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K338 N338 Biomuta DOID:9256 / colorectal cancer [ cosmic ]