iPTMnet Report for P08134 (RHOC)
Protein Information
| UniProt AC / UniProt ID | P08134 / RHOC_HUMAN |
| Protein Name | Rho-related GTP-binding protein RhoC precursor |
| Gene Name | Name: RHOC Synonyms:ARH9,ARHC; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P08134 |
| PRO Name | Rho-related GTP-binding protein RhoC (human) |
| Definition | A Rho-related GTP-binding protein RhoC that is encoded in the genome of human. |
| Short Label | hRHOC |
| Category | organism-gene |
P08134 (RHOC) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K7 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T19 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S26 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K27 | Sumoylation | score1 | PhosphoSitePlus | |||
| Y34 | O-Glycosylation | score2 | GlyGen | 24141704 | ||
| Y34 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T37 | O-Glycosylation | score2 | UniProt | 24905543 | ||
| T60 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y66 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S73 | Phosphorylation | score0 | RLIMS-P | 29279389 | ||
| K104 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C107 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
| K118 | Acetylation | score1 | PhosphoSitePlus | |||
| K118 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K119 | Methylation | score1 | PhosphoSitePlus | |||
| K119 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K135 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S152 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y156 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S160 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S73 | A73 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S73 | F73 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K118 | T118 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K119 | N119 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] |
DAG View