iPTMnet Report for P08134 (RHOC)
Protein Information
UniProt AC / UniProt ID | P08134 / RHOC_HUMAN |
Protein Name | Rho-related GTP-binding protein RhoC precursor |
Gene Name | Name: RHOC Synonyms:ARH9,ARHC; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P08134 |
PRO Name | Rho-related GTP-binding protein RhoC (human) |
Definition | A Rho-related GTP-binding protein RhoC that is encoded in the genome of human. |
Short Label | hRHOC |
Category | organism-gene |
P08134 (RHOC) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K7 | Ubiquitination | score1 | PhosphoSitePlus | |||
T19 | Phosphorylation | score1 | PhosphoSitePlus | |||
S26 | Phosphorylation | score1 | PhosphoSitePlus | |||
K27 | Sumoylation | score1 | PhosphoSitePlus | |||
Y34 | O-Glycosylation | score2 | GlyGen | 24141704 | ||
Y34 | Phosphorylation | score1 | PhosphoSitePlus | |||
T37 | O-Glycosylation | score2 | UniProt | 24905543 | ||
T60 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y66 | Phosphorylation | score1 | PhosphoSitePlus | |||
S73 | Phosphorylation | score0 | RLIMS-P | 29279389 | ||
K104 | Ubiquitination | score1 | PhosphoSitePlus | |||
C107 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
K118 | Acetylation | score1 | PhosphoSitePlus | |||
K118 | Ubiquitination | score1 | PhosphoSitePlus | |||
K119 | Methylation | score1 | PhosphoSitePlus | |||
K119 | Ubiquitination | score1 | PhosphoSitePlus | |||
K135 | Ubiquitination | score1 | PhosphoSitePlus | |||
S152 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y156 | Phosphorylation | score1 | PhosphoSitePlus | |||
S160 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S73 | A73 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S73 | F73 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K118 | T118 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K119 | N119 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] |