iPTMnet Report for P08123 (COL1A2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P08123 / CO1A2_HUMAN
Protein Name Collagen alpha-2(I) chain precursor
Gene Name Name: COL1A2
Organism Homo sapiens (Human)

PRO ID PR:P08123
DAG View
PRO Name collagen alpha-2(I) chain (human)
Definition A collagen alpha-2(I) chain that is encoded in the genome of human.
Short Label hCOL1A2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P08123 (COL1A2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K177 O-Glycosylation GlyGen 4319110
K198 Acetylation PhosphoSitePlus
T209 Phosphorylation PhosphoSitePlus
S251 Phosphorylation PhosphoSitePlus
S389 Phosphorylation PhosphoSitePlus
S401 Phosphorylation PhosphoSitePlus
S404 Phosphorylation PhosphoSitePlus
T632 O-Glycosylation GlyGen 30459171
S710 Phosphorylation PhosphoSitePlus
T860 O-Glycosylation GlyGen 30459171
T981 Phosphorylation PhosphoSitePlus
K1064 Acetylation PhosphoSitePlus
T1073 Phosphorylation PhosphoSitePlus
S1104 Phosphorylation PhosphoSitePlus
S1124 Phosphorylation PhosphoSitePlus
T1138 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T1138 Phosphorylation PhosphoSitePlus
S1141 Phosphorylation PhosphoSitePlus
T1148 Phosphorylation PhosphoSitePlus
S1155 Phosphorylation PhosphoSitePlus
N1267 N-Glycosylation GlyGen 23090970, 29741879, 24190977
S1295 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K177 N177 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S251 F251 Biomuta DOID:4159 / skin cancer [ cosmic ]
S404 P404 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S404 Y404 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T1148 I1148 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1155 Y1155 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]