iPTMnet Report for P07942 (LAMB1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P07942 / LAMB1_HUMAN
Protein Name Laminin subunit beta-1 precursor
Gene Name Name: LAMB1
Organism Homo sapiens (Human)

PRO ID PR:P07942
DAG View
PRO Name laminin subunit beta-1 (human)
Definition A laminin subunit beta-1 that is encoded in the genome of human.
Short Label hLAMB1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P07942 (LAMB1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S154 Phosphorylation HPRD   PhosphoSitePlus 20058876
K184 Ubiquitination PhosphoSitePlus
S195 Phosphorylation PhosphoSitePlus
K215 Sumoylation PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
Y220 Phosphorylation PhosphoSitePlus
S221 Phosphorylation PhosphoSitePlus
K229 Ubiquitination PhosphoSitePlus
T231 Phosphorylation PhosphoSitePlus
K239 Ubiquitination PhosphoSitePlus
T242 Phosphorylation HPRD   PhosphoSitePlus 19562805
N330 N-Glycosylation GlyGen 29391424
T369 Phosphorylation PhosphoSitePlus
N677 N-Glycosylation GlyGen 29741879, 29391424
C710 Methylation IEDB 31844290
T939 Phosphorylation HPRD 18767875
Y950 Phosphorylation HPRD 18767875
S953 Phosphorylation HPRD 18767875
C1009 Methylation IEDB 31844290
N1041 N-Glycosylation GlyGen 29741879
S1222 Phosphorylation PhosphoSitePlus
K1231 Ubiquitination PhosphoSitePlus
K1244 Ubiquitination PhosphoSitePlus
K1255 Ubiquitination PhosphoSitePlus
N1279 N-Glycosylation GlyGen   UniProt 16335952, 29741879, 19159218, ...29391424
S1280 O-Glycosylation GlyGen 34019948, 34725712, 35138101, ...30059200
S1280 Phosphorylation HPRD   PhosphoSitePlus 19413330
T1281 Phosphorylation HPRD   PhosphoSitePlus 19413330
T1290 Phosphorylation PhosphoSitePlus
K1310 Ubiquitination PhosphoSitePlus
R1315 Methylation PhosphoSitePlus
N1336 N-Glycosylation GlyGen 29391424
S1365 Phosphorylation PhosphoSitePlus
T1435 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
K1476 Ubiquitination PhosphoSitePlus
S1478 Phosphorylation PhosphoSitePlus   UniProt 26091039
S1496 Phosphorylation UniProt 26091039
S1520 Phosphorylation PhosphoSitePlus
N1542 N-Glycosylation GlyGen 29391424
K1611 Ubiquitination PhosphoSitePlus
S1666 Phosphorylation PhosphoSitePlus   UniProt 26091039
Y1671 Phosphorylation PhosphoSitePlus
T1678 O-Glycosylation GlyGen 25813380
S1682 Phosphorylation UniProt 26091039
S1735 Phosphorylation HPRD   PhosphoSitePlus 20068231
K1736 Acetylation PhosphoSitePlus
K1741 Ubiquitination PhosphoSitePlus
K1746 Acetylation PhosphoSitePlus
K1757 Ubiquitination PhosphoSitePlus
K1773 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N1279 N-Glycosylation PRO 29741879


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S154 F154 Biomuta [ cosmic ]
S195 F195 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1222 W1222 Biomuta DOID:1324 / lung cancer [ cosmic ]
K1255 N1255 Biomuta DOID:363 / uterine cancer [ icgc ]
K1310 E1310 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
R1315 W1315 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4362 / cervical cancer [ cosmic, icgc ]
R1315 Q1315 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1520 N1520 Biomuta DOID:1319 / brain cancer [ cosmic ]
S1735 N1735 Biomuta DOID:4159 / skin cancer [ cosmic ]