iPTMnet Report for P07864 (LDHC)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P07864 / LDHC_HUMAN
Protein Name L-lactate dehydrogenase C chain
Gene Name Name: LDHC
Synonyms:LDH3,LDHX;
Organism Homo sapiens (Human)

PRO ID PR:P07864
DAG View
PRO Name L-lactate dehydrogenase C chain (human)
Definition An L-lactate dehydrogenase C chain that is encoded in the genome of human.
Short Label hLDHC
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P07864 (LDHC) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T28 Phosphorylation PhosphoSitePlus
S38 Phosphorylation PhosphoSitePlus
K59 Acetylation PhosphoSitePlus
S73 Phosphorylation PhosphoSitePlus
S75 Phosphorylation PhosphoSitePlus
T95 Phosphorylation HPRD   PhosphoSitePlus 20068231
S137 Phosphorylation PhosphoSitePlus
S161 Phosphorylation PhosphoSitePlus
S167 Phosphorylation PhosphoSitePlus
R169 Methylation PhosphoSitePlus
T220 Phosphorylation PhosphoSitePlus
S222 Phosphorylation PhosphoSitePlus
K245 Ubiquitination PhosphoSitePlus
R269 Methylation PhosphoSitePlus
T275 Phosphorylation PhosphoSitePlus
K278 Methylation PhosphoSitePlus
S301 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20068231
T322 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T28 N28 Biomuta DOID:363 / uterine cancer [ icgc ]
S38 I38 Biomuta DOID:3571 / liver cancer [ cosmic ]
S161 R161 Biomuta DOID:4159 / skin cancer [ cosmic ]
S167 F167 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R169 H169 Biomuta DOID:363 / uterine cancer [ icgc ]
T220 M220 Biomuta [ cosmic ] DOID:10283 / prostate cancer [ cosmic, icgc ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
R269 K269 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]