Protein Information

Cytoscape View


UniProt AC / UniProt ID P07766 / CD3E_HUMAN
Protein Name T-cell surface glycoprotein CD3 epsilon chain precursor
Gene Name Name: CD3E
Synonyms:T3E;
Organism Homo sapiens (Human)

PRO ID PR:P07766
DAG View
PRO Name T-cell surface glycoprotein CD3 epsilon chain (human)
Definition A CD3 epsilon that is encoded in the genome of human.
Short Label hCD3E
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P07766 (CD3E) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K64 Ubiquitination PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
S77 Phosphorylation PhosphoSitePlus
S83 Phosphorylation PhosphoSitePlus
K85 Ubiquitination PhosphoSitePlus
K104 Ubiquitination PhosphoSitePlus
K177 Ubiquitination PhosphoSitePlus
Y188 Phosphorylation P06239 (LCK) , P06241 (FYN) HPRD   IntAct   phospho.ELM   PhosphoSitePlus   UniProt 15659558, 18555270, 16094384, ...9698567, 7761456, 15592455, 11855827, 19690332
Y199 Phosphorylation P06241 (FYN) , P06239 (LCK) HPRD   IntAct   phospho.ELM   PhosphoSitePlus   UniProt 15659558, 18555270, 16094384, ...9698567, 15144186, 18083107, 7761456, 11855827, 15592455, 12522270
S200 Phosphorylation HPRD   PhosphoSitePlus 15144186
Site PTM Type PTM Enzyme Score Source PMID
Y188 Phosphorylation PRO
Y199 Phosphorylation PRO


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000025777 (hCD3E/iso:1/SigPep-/Phos:1) pY188,pY199 PRO


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P07766 (CD3E) Y188 P43403 (ZAP70) unknown eFIP 7761456
Phosphorylation P07766 (CD3E) Y188 P29353 (SHC1) unknown eFIP 11855827
Phosphorylation P07766 (CD3E) Y199 P43403 (ZAP70) unknown eFIP 11855827
Phosphorylation P07766 (CD3E) Y188 P06239 (LCK) unknown eFIP 11855827
Phosphorylation P07766 (CD3E) Y188 P43405 (SYK) unknown eFIP 7761456
Phosphorylation P07766 (CD3E) Y188 P43405 (SYK) unknown eFIP 9698567