iPTMnet Report for P07477 (PRSS1)
Protein Information
| UniProt AC / UniProt ID | P07477 / TRY1_HUMAN |
| Protein Name | Serine protease 1 precursor |
| Gene Name | Name: PRSS1 Synonyms:TRP1,TRY1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P07477 |
| PRO Name | serine protease 1 (human) |
| Definition | A serine protease 1 that is encoded in the genome of human. |
| Short Label | hPRSS1 |
| Category | organism-gene |
DAG ViewP07477 (PRSS1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T8 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K92 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T103 | O-Glycosylation | score1 | GlyGen | 34105348 | ||
| K112 | Acetylation | score1 | PhosphoSitePlus | |||
| Y154 | Phosphorylation | score3 | HPRD phospho.ELM PhosphoSitePlus | 8683601 | ||
| K225 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K231 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T8 | S8 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| T8 | I8 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| K225 | E225 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K225 | T225 | Biomuta | DOID:3119 / gastrointestinal system cancer [ cosmic ] | |
| K225 | R225 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] |
