iPTMnet Report for P07437 (TUBB)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P07437 / TBB5_HUMAN
Protein Name Tubulin beta chain
Gene Name Name: TUBB
Synonyms:TUBB5;ORFNames:OK/SW-cl.56;
Organism Homo sapiens (Human)

PRO ID PR:P07437
DAG View
PRO Name tubulin beta chain (human)
Definition A tubulin beta chain that is encoded in the genome of human.
Short Label hTUBB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P07437 (TUBB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R2 Methylation PhosphoSitePlus
C12 S-Nitrosylation dbSNO 19483679
K19 Acetylation PhosphoSitePlus
K19 Methylation PhosphoSitePlus
K19 Ubiquitination PhosphoSitePlus
S25 Phosphorylation HPRD   PhosphoSitePlus 20068231
T33 Phosphorylation PhosphoSitePlus
T35 Phosphorylation PhosphoSitePlus
Y36 Phosphorylation HPRD   phospho.ELM   PRO   PhosphoSitePlus 15592455
S40 Phosphorylation PhosphoSitePlus
R46 Methylation PhosphoSitePlus
S48 Phosphorylation HPRD   PRO   PhosphoSitePlus 19664994, 19007248, 20068231, ...19691289
Y50 Phosphorylation HPRD   PhosphoSitePlus 20068231
Y51 Phosphorylation HPRD   PhosphoSitePlus 20068231
T55 Phosphorylation HPRD   PRO   PhosphoSitePlus   UniProt 23186163, 19007248, 19691289
K58 Acetylation PRO   PhosphoSitePlus   UniProt 19608861
K58 Methylation PhosphoSitePlus
K58 Sumoylation PhosphoSitePlus
K58 Ubiquitination PhosphoSitePlus
Y59 Phosphorylation PhosphoSitePlus
T72 Phosphorylation PhosphoSitePlus
S75 Phosphorylation PhosphoSitePlus
S78 Phosphorylation PhosphoSitePlus
S95 Phosphorylation PhosphoSitePlus
K103 Acetylation PhosphoSitePlus
K103 Sumoylation PhosphoSitePlus
K103 Ubiquitination PhosphoSitePlus
Y106 Phosphorylation PhosphoSitePlus
T107 Phosphorylation PhosphoSitePlus
S115 Phosphorylation PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
S126 Phosphorylation PhosphoSitePlus
T136 Phosphorylation PhosphoSitePlus
S138 Phosphorylation PhosphoSitePlus
T143 Phosphorylation PhosphoSitePlus
S145 Phosphorylation PhosphoSitePlus
T149 Phosphorylation PhosphoSitePlus
S153 Phosphorylation PhosphoSitePlus
K154 Ubiquitination PhosphoSitePlus
Y159 Phosphorylation PhosphoSitePlus
R162 Methylation PhosphoSitePlus
T166 Phosphorylation PhosphoSitePlus
S168 Phosphorylation PhosphoSitePlus
S172 Phosphorylation neXtProt   PhosphoSitePlus   UniProt 16371510
K174 Ubiquitination PhosphoSitePlus
Y183 Phosphorylation PhosphoSitePlus
T196 Phosphorylation PhosphoSitePlus
T199 Phosphorylation PhosphoSitePlus
Y200 Phosphorylation PhosphoSitePlus
Y208 Phosphorylation PhosphoSitePlus
K216 Acetylation PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
T218 Phosphorylation PhosphoSitePlus
T219 Phosphorylation PhosphoSitePlus
T221 Phosphorylation PhosphoSitePlus
Y222 Phosphorylation PhosphoSitePlus
S234 Phosphorylation PhosphoSitePlus
C239 S-Nitrosylation dbSNO 19483679, 25040305
K252 Acetylation PhosphoSitePlus
K252 Sumoylation PhosphoSitePlus
K252 Ubiquitination PhosphoSitePlus
T274 Phosphorylation PhosphoSitePlus
S275 Phosphorylation Q5TCY1 (TTBK1) HPRD   PhosphoSitePlus 7556643
R276 Methylation PhosphoSitePlus
S278 Phosphorylation PhosphoSitePlus
Y281 Phosphorylation PhosphoSitePlus
T285 Phosphorylation PhosphoSitePlus   UniProt 23186163
T290 Phosphorylation PhosphoSitePlus   UniProt 23186163
K297 Acetylation PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
C303 S-Nitrosylation dbSNO 25040305
Y310 Phosphorylation PhosphoSitePlus
T312 Phosphorylation PhosphoSitePlus
R318 Methylation PhosphoSitePlus
S322 Phosphorylation PhosphoSitePlus
K324 Acetylation PhosphoSitePlus
K324 Sumoylation PhosphoSitePlus
K324 Ubiquitination PhosphoSitePlus
K336 Acetylation PhosphoSitePlus
K336 Ubiquitination PhosphoSitePlus
S338 Phosphorylation PhosphoSitePlus
S339 Phosphorylation PhosphoSitePlus
Y340 Phosphorylation PRO   PhosphoSitePlus
K350 Sumoylation PhosphoSitePlus
K350 Ubiquitination PhosphoSitePlus
T351 Phosphorylation PhosphoSitePlus
K362 Ubiquitination PhosphoSitePlus
T366 Phosphorylation PhosphoSitePlus
S371 Phosphorylation PhosphoSitePlus
K379 Acetylation PhosphoSitePlus
K379 Ubiquitination PhosphoSitePlus
S382 Phosphorylation PhosphoSitePlus
T386 Phosphorylation PhosphoSitePlus
K392 Ubiquitination PhosphoSitePlus
T399 Phosphorylation PhosphoSitePlus
T409 Phosphorylation IntAct 24813628
Y422 Phosphorylation PhosphoSitePlus
Y425 Phosphorylation PhosphoSitePlus
T429 Phosphorylation HPRD   PRO   PhosphoSitePlus 19007248


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000036901 (hTUBB/Phos:1) pY340 PRO
PR:000036902 (hTUBB/Phos:2) pY340,pT429 PRO
PR:000036903 (hTUBB/AcPhos:1) acK58 PRO
PR:000036903 (hTUBB/AcPhos:1) pY36,pS48 PRO
PR:000036904 (hTUBB/AcPhos:2) acK58 PRO
PR:000036904 (hTUBB/AcPhos:2) pY36,pS48,pT55,pY340 PRO


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P07437 (TUBB) T409 P25098 (GRK2) unknown eFIP 24813628