iPTMnet Report for P07327 (ADH1A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P07327 / ADH1A_HUMAN
Protein Name Alcohol dehydrogenase 1A
Gene Name Name: ADH1A
Synonyms:ADH1;
Organism Homo sapiens (Human)

PRO ID PR:P07327
DAG View
PRO Name alcohol dehydrogenase 1A (human)
Definition An alcohol dehydrogenase 1A that is encoded in the genome of human.
Short Label hADH1A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P07327 (ADH1A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 3013304
S23 Phosphorylation HPRD   PhosphoSitePlus 20166139
S76 Phosphorylation PhosphoSitePlus
T82 Phosphorylation PhosphoSitePlus
Y111 Phosphorylation PhosphoSitePlus
Y150 Phosphorylation PhosphoSitePlus
T151 Phosphorylation PhosphoSitePlus
S165 Phosphorylation PhosphoSitePlus
T179 Phosphorylation PhosphoSitePlus
Y181 Phosphorylation PhosphoSitePlus
S207 Phosphorylation IEDB 32387766
Y247 Phosphorylation PhosphoSitePlus
K316 Acetylation PhosphoSitePlus
K324 Acetylation PhosphoSitePlus
K339 Acetylation PhosphoSitePlus
S342 Phosphorylation PhosphoSitePlus
K355 Acetylation PhosphoSitePlus
S365 Phosphorylation PhosphoSitePlus
K367 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S23 F23 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y150 * Biomuta DOID:1324 / lung cancer [ cosmic ]
Y150 H150 Biomuta DOID:1319 / brain cancer [ cosmic ]
S165 L165 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ]
S207 F207 Biomuta DOID:4159 / skin cancer [ cosmic ]
S207 C207 Biomuta DOID:1324 / lung cancer [ cosmic ]
S342 L342 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S365 C365 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K367 R367 Biomuta DOID:4159 / skin cancer [ cosmic ]