iPTMnet Report P07288 KLK3

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P07288 / KLK3_HUMAN
Protein Name	Prostate-specific antigen precursor
Gene Name	Name: KLK3 Synonyms:APS;
Organism	Homo sapiens (Human)

PRO ID	PR:P07288 DAG View
PRO Name	prostate-specific antigen (human)
Definition	A prostate-specific antigen that is encoded in the genome of human.
Short Label	hKLK3
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P07288 (KLK3) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	N69	N-Glycosylation		score3	GlyGen	26022737, 33167210, 17956937, ...33618028, 25327667, 24393138
	T143	Phosphorylation		score1	PhosphoSitePlus
	T167	Phosphorylation		score1	PhosphoSitePlus
	K251	Ubiquitination		score1	PhosphoSitePlus
	K254	Ubiquitination		score1	PhosphoSitePlus

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	N69	N-Glycosylation		score3	PRO	17956937, 25327667, 24393138
	T143	Phosphorylation		score0	HPRD	18077418
	T167	Phosphorylation		score0	HPRD	18077418

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	T143	Phosphorylation		score0	HPRD	18077418
	T167	Phosphorylation		score0	HPRD	18077418

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	T100	Phosphorylation		score0	HPRD	18077418
	T124	Phosphorylation		score0	HPRD	18077418

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
N69	K69	Biomuta		DOID:9256 / colorectal cancer [ cosmic ]
K251	*	Biomuta		DOID:9256 / colorectal cancer [ cosmic ]