iPTMnet Report for P07205 (PGK2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P07205 / PGK2_HUMAN
Protein Name Phosphoglycerate kinase 2
Gene Name Name: PGK2
Synonyms:PGKB;
Organism Homo sapiens (Human)

PRO ID PR:P07205
DAG View
PRO Name phosphoglycerate kinase 2 (human)
Definition A phosphoglycerate kinase 2 that is encoded in the genome of human.
Short Label hPGK2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P07205 (PGK2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K31 Acetylation PhosphoSitePlus
T35 Phosphorylation PhosphoSitePlus
S43 Phosphorylation PhosphoSitePlus
S62 Phosphorylation PhosphoSitePlus
Y76 Phosphorylation PhosphoSitePlus
S77 Phosphorylation PhosphoSitePlus
S87 Phosphorylation PhosphoSitePlus
K91 Acetylation PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
K131 Acetylation PhosphoSitePlus
K138 Acetylation PhosphoSitePlus
S153 Phosphorylation PhosphoSitePlus
S155 Phosphorylation PhosphoSitePlus
K156 Acetylation PhosphoSitePlus
K156 Ubiquitination PhosphoSitePlus
Y161 Phosphorylation PhosphoSitePlus
T168 Phosphorylation PhosphoSitePlus
S175 Phosphorylation HPRD 20068231
S186 Phosphorylation HPRD 20068231
Y196 Phosphorylation PhosphoSitePlus
Y242 Phosphorylation PhosphoSitePlus
K267 Acetylation PhosphoSitePlus
K267 Ubiquitination PhosphoSitePlus
K365 Acetylation PhosphoSitePlus
K388 Acetylation PhosphoSitePlus
K388 Ubiquitination PhosphoSitePlus
S399 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S43 F43 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ]
S62 R62 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S77 F77 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S87 F87 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K138 N138 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S155 F155 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
K156 T156 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S175 F175 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:4606 / bile duct cancer [ cosmic ]
Y196 C196 Biomuta DOID:363 / uterine cancer [ icgc ]
K267 N267 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
S399 I399 Biomuta DOID:1324 / lung cancer [ cosmic ]