iPTMnet Report for P07099 (EPHX1)
Protein Information
UniProt AC / UniProt ID | P07099 / HYEP_HUMAN |
Protein Name | Epoxide hydrolase 1 |
Gene Name | Name: EPHX1 Synonyms:EPHX,EPOX; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P07099 |
PRO Name | epoxide hydrolase 1 (human) |
Definition | An epoxide hydrolase 1 that is encoded in the genome of human. |
Short Label | hEPHX1 |
Category | organism-gene |
P07099 (EPHX1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S47 | Phosphorylation | score1 | PhosphoSitePlus | |||
K52 | Ubiquitination | score1 | PhosphoSitePlus | |||
T55 | Phosphorylation | score1 | PhosphoSitePlus | |||
S56 | Phosphorylation | score1 | PhosphoSitePlus | |||
K91 | Ubiquitination | score1 | PhosphoSitePlus | |||
K92 | Ubiquitination | score1 | PhosphoSitePlus | |||
S95 | Phosphorylation | score1 | PhosphoSitePlus | |||
K104 | Acetylation | score1 | PhosphoSitePlus | |||
K105 | Ubiquitination | score1 | PhosphoSitePlus | |||
K117 | Methylation | score1 | PhosphoSitePlus | |||
K119 | Methylation | score1 | PhosphoSitePlus | |||
K131 | Acetylation | score1 | PhosphoSitePlus | |||
K168 | Ubiquitination | score1 | PhosphoSitePlus | |||
S173 | Phosphorylation | score1 | PhosphoSitePlus | |||
K196 | Ubiquitination | score1 | PhosphoSitePlus | |||
K197 | Ubiquitination | score1 | PhosphoSitePlus | |||
T204 | Phosphorylation | score1 | PhosphoSitePlus | |||
K210 | Acetylation | score1 | PhosphoSitePlus | |||
Y283 | Phosphorylation | score1 | PhosphoSitePlus | |||
K286 | Ubiquitination | score1 | PhosphoSitePlus | |||
K288 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y291 | Phosphorylation | score1 | PhosphoSitePlus | |||
S297 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y299 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y339 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y361 | Phosphorylation | score1 | PhosphoSitePlus | |||
K386 | Acetylation | score1 | PhosphoSitePlus | |||
K386 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y393 | Phosphorylation | score1 | PhosphoSitePlus | |||
T408 | Phosphorylation | score1 | PhosphoSitePlus | |||
S422 | Phosphorylation | score0 | HPRD | 20068231 | ||
Y423 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y425 | Phosphorylation | score1 | PhosphoSitePlus | |||
S450 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S47 | I47 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S56 | A56 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
K197 | T197 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
K210 | R210 | Biomuta | DOID:3953 / adrenal gland cancer [ cosmic ] | |
Y283 | N283 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
Y291 | H291 | Biomuta | DOID:263 / kidney cancer [ icgc ] | |
Y339 | C339 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
T408 | K408 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
T408 | M408 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ] | |
Y423 | N423 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |