Protein Information

Cytoscape View


UniProt AC / UniProt ID P06737 / PYGL_HUMAN
Protein Name Glycogen phosphorylase, liver form
Gene Name Name: PYGL
Organism Homo sapiens (Human)

PRO ID PR:P06737
DAG View
PRO Name glycogen phosphorylase, liver form (human)
Definition A glycogen phosphorylase, liver form that is encoded in the genome of human.
Short Label hPYGL
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P06737 (PYGL) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330
K3 Ubiquitination PhosphoSitePlus
T6 Phosphorylation PhosphoSitePlus
K10 Ubiquitination PhosphoSitePlus
S15 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17081983, 10949035
K29 Acetylation PhosphoSitePlus
K29 Ubiquitination PhosphoSitePlus
K30 Ubiquitination PhosphoSitePlus
S31 Phosphorylation PhosphoSitePlus
T39 Phosphorylation PhosphoSitePlus
K42 Ubiquitination PhosphoSitePlus
Y75 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
Y76 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
R82 Methylation PhosphoSitePlus
Y85 Phosphorylation PhosphoSitePlus
Y114 Phosphorylation PhosphoSitePlus
K170 Ubiquitination PhosphoSitePlus
Y186 Phosphorylation PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
S193 Phosphorylation PhosphoSitePlus
Y204 Phosphorylation PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
R248 Methylation PhosphoSitePlus
Y263 Phosphorylation PhosphoSitePlus
Y281 Phosphorylation PhosphoSitePlus
K290 Ubiquitination PhosphoSitePlus
K295 Ubiquitination PhosphoSitePlus
K316 Ubiquitination PhosphoSitePlus
K359 Ubiquitination PhosphoSitePlus
S363 Phosphorylation PhosphoSitePlus
K364 Ubiquitination PhosphoSitePlus
K371 Ubiquitination PhosphoSitePlus
K395 Ubiquitination PhosphoSitePlus
Y405 Phosphorylation PhosphoSitePlus
K410 Ubiquitination PhosphoSitePlus
R414 Methylation PhosphoSitePlus
K421 Ubiquitination PhosphoSitePlus
S430 Phosphorylation PhosphoSitePlus
K438 Ubiquitination PhosphoSitePlus
S450 Phosphorylation PhosphoSitePlus
K465 Ubiquitination PhosphoSitePlus
K470 Acetylation PhosphoSitePlus
K470 Ubiquitination PhosphoSitePlus
S473 Phosphorylation PhosphoSitePlus
K479 Acetylation PhosphoSitePlus
K479 Ubiquitination PhosphoSitePlus
K483 Ubiquitination PhosphoSitePlus
K514 Ubiquitination PhosphoSitePlus
S517 Phosphorylation PhosphoSitePlus
T520 Phosphorylation PhosphoSitePlus
K521 Ubiquitination PhosphoSitePlus
S524 Phosphorylation PhosphoSitePlus
K545 Ubiquitination PhosphoSitePlus
S547 Phosphorylation PhosphoSitePlus
K555 Ubiquitination PhosphoSitePlus
K557 Ubiquitination PhosphoSitePlus
K569 Ubiquitination PhosphoSitePlus
K575 Acetylation PhosphoSitePlus
K609 Ubiquitination PhosphoSitePlus
Y614 Phosphorylation PhosphoSitePlus
S626 Phosphorylation PhosphoSitePlus
S639 Phosphorylation PhosphoSitePlus   UniProt 24275569
K640 Ubiquitination PhosphoSitePlus
K642 Ubiquitination PhosphoSitePlus
K656 Ubiquitination PhosphoSitePlus
K724 Acetylation PhosphoSitePlus
K724 Ubiquitination PhosphoSitePlus
K725 Ubiquitination PhosphoSitePlus
K730 Ubiquitination PhosphoSitePlus
S752 Phosphorylation PhosphoSitePlus
K754 Ubiquitination PhosphoSitePlus
Y778 Phosphorylation PhosphoSitePlus
K783 Ubiquitination PhosphoSitePlus
K787 Ubiquitination PhosphoSitePlus
K796 Ubiquitination PhosphoSitePlus
K804 Ubiquitination PhosphoSitePlus
K811 Ubiquitination PhosphoSitePlus
R816 Methylation PhosphoSitePlus
K819 Ubiquitination PhosphoSitePlus
K834 Acetylation PhosphoSitePlus
K834 Ubiquitination PhosphoSitePlus
S836 Phosphorylation PhosphoSitePlus
S838 Phosphorylation PhosphoSitePlus
K843 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S15 Phosphorylation HPRD 17081983
Y75 Phosphorylation HPRD 18083107
Y76 Phosphorylation HPRD 18083107


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 V2 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
K30 N30 Biomuta DOID:1324 / lung cancer [ tcga ]
Y114 * Biomuta DOID:1909 / melanoma [ cosmic ]
K170 T170 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
K170 N170 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
T520 M520 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K555 T555 Biomuta DOID:1909 / melanoma [ cosmic ]
S639 N639 Biomuta DOID:1324 / lung cancer [ tcga ]
K724 N724 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
S752 P752 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
S752 Y752 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
K819 * Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]