iPTMnet Report for P06732 (CKM)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P06732 / KCRM_HUMAN
Protein Name Creatine kinase M-type
Gene Name Name: CKM
Synonyms:CKMM;
Organism Homo sapiens (Human)

PRO ID PR:P06732
DAG View
PRO Name creatine kinase M-type (human)
Definition A creatine kinase M-type that is encoded in the genome of human.
Short Label hCKM
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P06732 (CKM) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y14 Phosphorylation PhosphoSitePlus
Y20 Phosphorylation PhosphoSitePlus
S24 Phosphorylation PhosphoSitePlus
T35 Phosphorylation PhosphoSitePlus
Y39 Phosphorylation PhosphoSitePlus
K40 Acetylation PhosphoSitePlus
K41 Acetylation PhosphoSitePlus
Y125 Phosphorylation PhosphoSitePlus
S128 Phosphorylation PhosphoSitePlus
S129 Phosphorylation PhosphoSitePlus
S136 Phosphorylation PhosphoSitePlus
Y140 Phosphorylation PhosphoSitePlus
T141 Phosphorylation PhosphoSitePlus
S164 Phosphorylation PhosphoSitePlus
T166 Phosphorylation PhosphoSitePlus
K170 Acetylation PhosphoSitePlus
Y173 Phosphorylation PhosphoSitePlus
Y174 Phosphorylation PhosphoSitePlus
S178 Phosphorylation PhosphoSitePlus
T180 Phosphorylation PhosphoSitePlus
S199 Phosphorylation PhosphoSitePlus
R215 Methylation PhosphoSitePlus
S224 Phosphorylation PhosphoSitePlus
K247 Acetylation PhosphoSitePlus
K265 Acetylation PhosphoSitePlus
Y279 Phosphorylation PhosphoSitePlus
T313 Phosphorylation PhosphoSitePlus
T322 Phosphorylation PhosphoSitePlus
T327 Phosphorylation PhosphoSitePlus
S332 Phosphorylation PhosphoSitePlus
K365 Acetylation PhosphoSitePlus
S372 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T35 I35 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K40 R40 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K41 Q41 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S136 R136 Biomuta DOID:263 / kidney cancer [ cosmic ]
T166 M166 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:5158 / pleural cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
T166 A166 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T180 M180 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]