iPTMnet Report for P06729 (CD2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P06729 / CD2_HUMAN
Protein Name T-cell surface antigen CD2 precursor
Gene Name Name: CD2
Synonyms:SRBC;
Organism Homo sapiens (Human)

PRO ID PR:P06729
DAG View
PRO Name T-cell surface antigen CD2 (human)
Definition A CD2 molecule that is encoded in the genome of human.
Short Label hCD2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P06729 (CD2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T77 O-Glycosylation GlyGen 29351928
N89 N-Glycosylation GlyGen   UniProt 7994575
T99 Phosphorylation PhosphoSitePlus
K106 Ubiquitination PhosphoSitePlus
K125 Ubiquitination PhosphoSitePlus
N141 N-Glycosylation GlyGen   UniProt 7994575
N150 N-Glycosylation GlyGen   UniProt 7994575
K166 Ubiquitination PhosphoSitePlus
T173 Phosphorylation PhosphoSitePlus
T258 Phosphorylation PhosphoSitePlus
K264 Ubiquitination PhosphoSitePlus
S290 Phosphorylation PhosphoSitePlus
S294 Phosphorylation PhosphoSitePlus
K310 Ubiquitination PhosphoSitePlus
K324 Ubiquitination PhosphoSitePlus
S345 Phosphorylation PhosphoSitePlus
S347 Phosphorylation PhosphoSitePlus
S350 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N89 N-Glycosylation PRO 1385399, 7544493, 7688025


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:000036596 (hCD2/iso:1/SigPep-/NGlyco:1) Interaction PR:P19256 (hCD58) PRO 7544493, 7688025
PR:P19256 (hCD58) Interaction PR:000036596 (hCD2/iso:1/SigPep-/NGlyco:1) PRO 7544493, 7688025


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K125 R125 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S290 F290 Biomuta DOID:3571 / liver cancer [ cosmic ]
S294 I294 Biomuta DOID:9256 / colorectal cancer [ icgc ] DOID:3571 / liver cancer [ cosmic ]
S350 F350 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S350 C350 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]