iPTMnet Report for P06127 (CD5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P06127 / CD5_HUMAN
Protein Name T-cell surface glycoprotein CD5 precursor
Gene Name Name: CD5
Synonyms:LEU1;
Organism Homo sapiens (Human)

PRO ID PR:P06127
DAG View
PRO Name T-cell surface glycoprotein CD5 (human)
Definition A T-cell surface glycoprotein CD5 that is encoded in the genome of human.
Short Label hCD5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P06127 (CD5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K79 Ubiquitination PhosphoSitePlus
S186 Phosphorylation PhosphoSitePlus
K211 Ubiquitination PhosphoSitePlus
N241 N-Glycosylation GlyGen 24190977
K273 Ubiquitination PhosphoSitePlus
K346 Ubiquitination PhosphoSitePlus
K361 Ubiquitination PhosphoSitePlus
T421 Phosphorylation PhosphoSitePlus
S428 Phosphorylation PhosphoSitePlus
T434 Phosphorylation P05771 (PRKCB) , P17252 (PRKCA) , P05129 (PRKCG) HPRD   phospho.ELM   PhosphoSitePlus   Signor 11123317
T436 Phosphorylation P17252 (PRKCA) , P05129 (PRKCG) , P05771 (PRKCB) HPRD   phospho.ELM   PhosphoSitePlus   Signor 11123317
S439 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 12522270, 15144186
T445 Phosphorylation PhosphoSitePlus
S447 Phosphorylation PhosphoSitePlus
Y453 Phosphorylation P06241 (FYN) , P06239 (LCK) HPRD   IntAct   phospho.ELM   PhosphoSitePlus   Signor   UniProt 15659558, 15144186, 9603468, ...12522270, 19690332, 11298344
S454 Phosphorylation HPRD   PhosphoSitePlus 15144186
S460 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 12522270, 15144186
Y465 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 11751967, 9079809
S476 Phosphorylation PhosphoSitePlus
S482 Phosphorylation P68400 (CSNK2A1) HPRD   phospho.ELM   PhosphoSitePlus   Signor 9834084
S483 Phosphorylation P68400 (CSNK2A1) HPRD   phospho.ELM   PhosphoSitePlus   Signor   UniProt 19690332, 9834084
S485 Phosphorylation P68400 (CSNK2A1) HPRD   phospho.ELM   PhosphoSitePlus   Signor   UniProt 9834084, 19690332
Y487 Phosphorylation P06241 (FYN) , P06239 (LCK) HPRD   IntAct   phospho.ELM   PhosphoSitePlus   Signor 11298344, 9079809


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T421 M421 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]
T434 M434 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S447 P447 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
Y453 * Biomuta DOID:1319 / brain cancer [ cosmic ]
Y465 F465 Biomuta DOID:3571 / liver cancer [ cosmic ]
S476 Y476 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S483 F483 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S485 G485 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S485 C485 Biomuta [ cosmic ]