iPTMnet Report for P05997 (COL5A2)
Protein Information
| UniProt AC / UniProt ID | P05997 / CO5A2_HUMAN |
| Protein Name | Collagen alpha-2(V) chain precursor |
| Gene Name | Name: COL5A2 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P05997 |
| PRO Name | collagen alpha-2(V) chain (human) |
| Definition | A collagen alpha-2(V) chain that is encoded in the genome of human. |
| Short Label | hCOL5A2 |
| Category | organism-gene |
P05997 (COL5A2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S139 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S188 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| S283 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T326 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S376 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T575 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T772 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K785 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T790 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T901 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T908 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S913 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T988 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T989 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1015 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
| N1262 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
| S1276 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1277 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1281 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1284 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N1400 | N-Glycosylation | score1 | GlyGen | 23090970, 29741879, 24190977 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S139 | L139 | Biomuta | DOID:1612 / breast cancer [ icgc ] | |
| S283 | F283 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
| T772 | I772 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T790 | K790 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| T988 | M988 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] | |
| T988 | K988 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
| T1015 | A1015 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| N1262 | I1262 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] |
DAG View