iPTMnet Report for P05981 (HPN)
Protein Information
| UniProt AC / UniProt ID | P05981 / HEPS_HUMAN |
| Protein Name | Serine protease hepsin |
| Gene Name | Name: HPN Synonyms:TMPRSS1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P05981 |
| PRO Name | serine protease hepsin (human) |
| Definition | A serine protease hepsin that is encoded in the genome of human. |
| Short Label | hHPN |
| Category | organism-gene |
DAG ViewP05981 (HPN) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| N112 | N-Glycosylation | score2 | GlyGen UniProt | 19159218 | ||
| Y341 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S353 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S362 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S364 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K386 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K392 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S362 | G362 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S364 | C364 | Biomuta | DOID:2394 / ovarian cancer [ icgc ] |
