iPTMnet Report for P05976 (MYL1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P05976 / MYL1_HUMAN
Protein Name Myosin light chain 1/3, skeletal muscle isoform
Gene Name Name: MYL1
Organism Homo sapiens (Human)

PRO ID PR:P05976
DAG View
PRO Name myosin light chain 1/3, skeletal muscle isoform (human)
Definition A myosin light chain 1/3, skeletal muscle isoform that is encoded in the genome of human.
Short Label hMYL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P05976 (MYL1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T65 Phosphorylation PhosphoSitePlus
S68 Phosphorylation PhosphoSitePlus
S73 Phosphorylation PhosphoSitePlus
T87 Phosphorylation PhosphoSitePlus
S99 Phosphorylation PhosphoSitePlus
K141 Acetylation PhosphoSitePlus
K141 Ubiquitination PhosphoSitePlus
K162 Acetylation PhosphoSitePlus
S178 Phosphorylation PhosphoSitePlus
C181 S-Nitrosylation dbSNO 19452190, 22178444


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S68 F68 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T87 I87 Biomuta DOID:363 / uterine cancer [ icgc ]
S99 R99 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K141 N141 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S178 Y178 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]