iPTMnet Report for P05813 (CRYBA1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P05813 / CRBA1_HUMAN
Protein Name Beta-crystallin A3
Gene Name Name: CRYBA1
Synonyms:CRYB1;
Organism Homo sapiens (Human)

PRO ID PR:P05813
DAG View
PRO Name beta-crystallin A3 (human)
Definition A beta-crystallin A3 that is encoded in the genome of human.
Short Label hCRYBA1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P05813 (CRYBA1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 8999933, 15576560
E2 Acetylation UniProt 8999933, 15576560
T15 Phosphorylation PhosphoSitePlus
C82 Methylation UniProt 15576560
S112 Phosphorylation PhosphoSitePlus
C117 Methylation UniProt 15576560
K122 Acetylation PhosphoSitePlus
K125 Acetylation PhosphoSitePlus
T127 Phosphorylation phospho.ELM   PhosphoSitePlus 12060738
K131 Acetylation PhosphoSitePlus
R137 Methylation PhosphoSitePlus
S160 Phosphorylation phospho.ELM   PhosphoSitePlus 12060738
Y179 Phosphorylation PhosphoSitePlus
Y181 Phosphorylation PhosphoSitePlus
C185 Methylation UniProt 15576560
T204 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T127 Phosphorylation HPRD 12060738
S160 Phosphorylation HPRD 12060738


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
C117 S117 Biomuta DOID:3571 / liver cancer [ cosmic ]
K131 E131 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]
R137 H137 Biomuta DOID:363 / uterine cancer [ icgc ]