iPTMnet Report for P05543 (SERPINA7)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P05543 / THBG_HUMAN
Protein Name Thyroxine-binding globulin precursor
Gene Name Name: SERPINA7
Synonyms:TBG;
Organism Homo sapiens (Human)

PRO ID PR:P05543
DAG View
PRO Name thyroxine-binding globulin (human)
Definition A thyroxine-binding globulin that is encoded in the genome of human.
Short Label hSERPINA7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P05543 (SERPINA7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N36 N-Glycosylation GlyGen   UniProt 16335952, 34725484, 30237853, ...23090970, 29391424, 19838169, 29741879, 29671580
T38 Phosphorylation PhosphoSitePlus
Y40 Phosphorylation PhosphoSitePlus
S164 Phosphorylation PhosphoSitePlus
N165 N-Glycosylation GlyGen   UniProt 16335952, 23090970, 29741879, ...29391424, 34725484
S175 Phosphorylation PhosphoSitePlus
T181 Phosphorylation PhosphoSitePlus
N253 N-Glycosylation GlyGen 29741879
S373 O-Glycosylation GlyGen 30459171
S390 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N36 N-Glycosylation PRO 19838169, 29671580


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y40 H40 Biomuta DOID:363 / uterine cancer [ icgc ]
S373 L373 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ]
S390 Y390 Biomuta DOID:363 / uterine cancer [ icgc ]