iPTMnet Report for P05455 (SSB)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P05455 / LA_HUMAN
Protein Name Lupus La protein
Gene Name Name: SSB
Organism Homo sapiens (Human)

PRO ID PR:P05455
DAG View
PRO Name lupus La protein (human)
Definition A lupus La protein that is encoded in the genome of human.
Short Label hSSB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P05455 (SSB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K9 Ubiquitination PhosphoSitePlus
C18 Methylation IEDB 31844290
Y23 Phosphorylation PhosphoSitePlus
Y24 Phosphorylation PhosphoSitePlus
K37 Ubiquitination PhosphoSitePlus
K41 Sumoylation PhosphoSitePlus
K41 Ubiquitination PhosphoSitePlus
K74 Ubiquitination PhosphoSitePlus
K76 Sumoylation PhosphoSitePlus
K76 Ubiquitination PhosphoSitePlus
S83 Phosphorylation PhosphoSitePlus
K86 Sumoylation PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
S92 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 20230923, 19651622, ...18669648, 20068231
S94 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 18669648, 23186163, ...20230923
K95 Acetylation PhosphoSitePlus
K95 Ubiquitination PhosphoSitePlus
Y104 Phosphorylation PhosphoSitePlus
K105 Sumoylation PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
K116 Acetylation PhosphoSitePlus   UniProt 19608861
K116 Sumoylation PhosphoSitePlus
K116 Ubiquitination PhosphoSitePlus
T120 Phosphorylation PhosphoSitePlus   UniProt 23186163
K128 Acetylation PhosphoSitePlus   UniProt 19608861
K128 Ubiquitination PhosphoSitePlus
K165 Acetylation PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
K174 Ubiquitination PhosphoSitePlus
K176 Ubiquitination PhosphoSitePlus
T178 Phosphorylation HPRD   PhosphoSitePlus 20068231
K185 Acetylation PhosphoSitePlus
K185 Sumoylation PhosphoSitePlus
Y188 Phosphorylation PhosphoSitePlus
K191 Methylation PhosphoSitePlus
K200 Sumoylation PhosphoSitePlus
K208 Sumoylation PhosphoSitePlus
K208 Ubiquitination PhosphoSitePlus
K216 Acetylation PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
K224 Ubiquitination PhosphoSitePlus
S225 Phosphorylation PhosphoSitePlus   UniProt 23186163
K229 Ubiquitination PhosphoSitePlus
C232 Methylation IEDB 31844290
C232 S-Nitrosylation dbSNO 19483679
K235 Ubiquitination PhosphoSitePlus
R266 Methylation PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
K276 Ubiquitination PhosphoSitePlus
K280 Acetylation PhosphoSitePlus
K285 Acetylation PhosphoSitePlus
K287 Ubiquitination PhosphoSitePlus
K299 Ubiquitination PhosphoSitePlus
T302 Phosphorylation HPRD   neXtProt   phospho.ELM   PhosphoSitePlus 18836485, 10715123
T302 Phosphorylation P31749 (AKT1) neXtProt 18836485
K312 Ubiquitination PhosphoSitePlus
S325 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 10715123
K328 Acetylation PhosphoSitePlus   UniProt 19608861
K328 Ubiquitination PhosphoSitePlus
K352 Acetylation PhosphoSitePlus
K352 Ubiquitination PhosphoSitePlus
K354 Acetylation PhosphoSitePlus
K354 Ubiquitination PhosphoSitePlus
K360 Acetylation PhosphoSitePlus   UniProt 19608861
K361 Acetylation PhosphoSitePlus
T362 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 10715123, 19651622, ...24275569, 20166139, 20068231
S366 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   Signor   UniProt 18707149, 18452278, 18691976, ...21406692, 23186163, 9054510, 18257391, 18318008, 19690332, 19413330, 19651622, 15485924, 18491316, 17287340, 18212344, 16083285, 10715123, 17081983, 19664995, 18669648, 20166139, 19415658, 20068231, 17924679
S366 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   Signor 15485924, 18257391, 9054510
T379 Phosphorylation HPRD   PhosphoSitePlus 18452278
T389 Phosphorylation PhosphoSitePlus
K391 Acetylation PhosphoSitePlus
K397 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S94 I94 Biomuta DOID:1324 / lung cancer [ cosmic ]
K166 R166 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K191 N191 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S225 F225 Biomuta DOID:363 / uterine cancer [ cosmic ]
C232 W232 Biomuta DOID:1612 / breast cancer [ icgc ]
K235 T235 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K299 R299 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S366 I366 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T379 A379 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]