iPTMnet Report for P05423 (POLR3D)
Protein Information
| UniProt AC / UniProt ID | P05423 / RPC4_HUMAN |
| Protein Name | DNA-directed RNA polymerase III subunit RPC4 |
| Gene Name | Name: POLR3D Synonyms:BN51,BN51T; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P05423 |
| PRO Name | DNA-directed RNA polymerase III subunit RPC4 (human) |
| Definition | A DNA-directed RNA polymerase III subunit RPC4 that is encoded in the genome of human. |
| Short Label | hPOLR3D |
| Category | organism-gene |
P05423 (POLR3D) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S2 | Acetylation | score1 | UniProt | 22814378 | ||
| S2 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R17 | Methylation | score1 | PhosphoSitePlus | |||
| T21 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R24 | Methylation | score1 | PhosphoSitePlus | |||
| R29 | Methylation | score1 | PhosphoSitePlus | |||
| R30 | Methylation | score1 | PhosphoSitePlus | |||
| T36 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S42 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| T59 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K78 | Sumoylation | score1 | PhosphoSitePlus | |||
| R90 | Methylation | score1 | PhosphoSitePlus | |||
| R95 | Methylation | score2 | PhosphoSitePlus UniProt | 24129315 | ||
| R97 | Methylation | score2 | PhosphoSitePlus UniProt | 24129315 | ||
| R99 | Methylation | score2 | PhosphoSitePlus UniProt | 24129315 | ||
| S105 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S107 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S130 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K141 | Sumoylation | score1 | PhosphoSitePlus | |||
| K141 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K152 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K190 | Sumoylation | score1 | PhosphoSitePlus | |||
| K199 | Sumoylation | score1 | PhosphoSitePlus | |||
| K199 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K206 | Sumoylation | score1 | PhosphoSitePlus | |||
| K218 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K220 | Sumoylation | score1 | PhosphoSitePlus | |||
| K247 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S250 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
| K285 | Sumoylation | score1 | PhosphoSitePlus | |||
| K285 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K288 | Sumoylation | score1 | PhosphoSitePlus | |||
| K302 | Sumoylation | score1 | PhosphoSitePlus | |||
| K302 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K310 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C316 | Methylation | score1 | IEDB | 31844290 | ||
| K328 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K380 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K382 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S386 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 17081983 | ||
| K396 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| R17 | Q17 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| R90 | Q90 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| R90 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] | |
| R95 | * | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
| R97 | * | Biomuta | DOID:363 / uterine cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] | |
| R99 | G99 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S130 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S250 | Y250 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| K288 | R288 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K382 | T382 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
DAG View