Protein Information

Cytoscape View


UniProt AC / UniProt ID P05386 / RLA1_HUMAN
Protein Name Large ribosomal subunit protein P1
Gene Name Name: RPLP1
Synonyms:RRP1;
Organism Homo sapiens (Human)

PRO ID PR:P05386
DAG View
PRO Name 60S acidic ribosomal protein P1 (human)
Definition A 60S acidic ribosomal protein P1 that is encoded in the genome of human.
Short Label hRPLP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P05386 (RPLP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22223895, 25944712
S3 Phosphorylation PhosphoSitePlus
S5 Phosphorylation PhosphoSitePlus
C9 Methylation IEDB 31844290
Y11 Phosphorylation PhosphoSitePlus
S12 Phosphorylation PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus
K49 Methylation PhosphoSitePlus
K49 Ubiquitination PhosphoSitePlus
S58 Phosphorylation PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus   UniProt 36638793
K93 Ubiquitination PhosphoSitePlus   UniProt 36638793
S101 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 16083285, 18088087, 16807684, ...18669648, 14997482, 17287340
S104 Phosphorylation phospho.ELM   PhosphoSitePlus 16083285, 17287340, 16964243, ...16097034, 18669648, 14729942, 18088087
Site PTM Type PTM Enzyme Score Source PMID
S5 Phosphorylation HPRD 17924679
Y11 Phosphorylation HPRD 17924679
S12 Phosphorylation HPRD 17924679
S101 Phosphorylation HPRD 19413330, 18491316, 18088087, ...18767875, 19664994, 19664995, 18452278, 19651622, 18669648, 20187088, 14997482, 17287340, 16565220, 19415658, 20068231, 20058876
S104 Phosphorylation HPRD 19413330, 18491316, 18088087, ...16964243, 18767875, 19664994, 19664995, 18452278, 19651622, 18669648, 20187088, 20058876, 18707149, 14729942, 17287340, 16565220, 19415658, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S76 Phosphorylation HPRD 19413330, 18491316, 18088087, ...18767875, 19664994, 19664995, 18452278, 19651622, 18669648, 20187088, 14997482, 17287340, 16565220, 19415658, 20068231, 20058876
S79 Phosphorylation HPRD 19413330, 18491316, 18088087, ...16964243, 18767875, 19664994, 19664995, 18452278, 19651622, 18669648, 20187088, 20058876, 18707149, 14729942, 17287340, 16565220, 19415658, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S76 F76 Biomuta DOID:4159 / skin cancer [ cosmic ]
S101 F101 Biomuta DOID:4159 / skin cancer [ cosmic ]