iPTMnet Report for P05362 (ICAM1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P05362 / ICAM1_HUMAN
Protein Name Intercellular adhesion molecule 1 precursor
Gene Name Name: ICAM1
Organism Homo sapiens (Human)

PRO ID PR:P05362
DAG View
PRO Name intercellular adhesion molecule 1 (human)
Definition An intercellular adhesion molecule 1 that is encoded in the genome of human.
Short Label hICAM1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P05362 (ICAM1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S43 Phosphorylation PhosphoSitePlus
T62 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T62 Phosphorylation PhosphoSitePlus
N95 N-Glycosylation GlyGen 24190977
N130 N-Glycosylation GlyGen   UniProt 9539702, 12526797, 24190977
N145 N-Glycosylation GlyGen   UniProt 24190977, 23090970, 19349973, ...19139490, 9539702, 12526797
N183 N-Glycosylation GlyGen   UniProt 23090970, 9539702, 12526797, ...24190977
N202 N-Glycosylation GlyGen   UniProt 9539702, 12526797, 19159218, ...9539703
Y207 Phosphorylation PhosphoSitePlus
T211 Phosphorylation PhosphoSitePlus
T217 Phosphorylation PhosphoSitePlus
S223 Phosphorylation PhosphoSitePlus
N267 N-Glycosylation GlyGen   UniProt 16335952, 19159218, 24190977, ...23090970, 19349973, 15099525, 29741879
S275 Phosphorylation PhosphoSitePlus
C290 Methylation IEDB 31844290
N296 N-Glycosylation GlyGen   UniProt 15099525
S323 Phosphorylation HPRD 20068231
K359 Ubiquitination PhosphoSitePlus
N385 N-Glycosylation GlyGen   UniProt 15099525, 24190977
Y394 Phosphorylation RLIMS-P 22433250
N406 N-Glycosylation GlyGen 24190977
N412 N-Glycosylation GlyGen 24190977
Y501 Phosphorylation phospho.ELM   PhosphoSitePlus 14973144
Y512 Phosphorylation phospho.ELM   PhosphoSitePlus 14973144
K519 Ubiquitination PhosphoSitePlus
T521 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
K524 Ubiquitination PhosphoSitePlus
T527 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
T530 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T62 I62 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
N145 K145 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S223 T223 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S275 L275 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y512 H512 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T530 M530 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]