iPTMnet Report for P05177 (CYP1A2)
Protein Information
| UniProt AC / UniProt ID | P05177 / CP1A2_HUMAN |
| Protein Name | Cytochrome P450 1A2 |
| Gene Name | Name: CYP1A2 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P05177 |
| PRO Name | cytochrome P450 1A2 (human) |
| Definition | A cytochrome P450 1A2 that is encoded in the genome of human. |
| Short Label | hCYP1A2 |
| Category | organism-gene |
DAG ViewP05177 (CYP1A2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| Y72 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S82 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20166139 | ||
| T267 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y272 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S279 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S298 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T349 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T438 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S82 | F82 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S82 | C82 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| Y272 | F272 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| Y272 | * | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
| T438 | S438 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] |
