iPTMnet Report for P05156 (CFI)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P05156 / CFAI_HUMAN
Protein Name Complement factor I precursor
Gene Name Name: CFI
Synonyms:IF;
Organism Homo sapiens (Human)

PRO ID PR:P05156
DAG View
PRO Name complement factor I (human)
Definition A complement factor I that is encoded in the genome of human.
Short Label hCFI
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P05156 (CFI) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y22 Phosphorylation PhosphoSitePlus
N70 N-Glycosylation GlyGen   UniProt 16335952, 23090970, 21768352, ...29391424, 29741879
S81 Phosphorylation IEDB 31848261
S90 Phosphorylation PhosphoSitePlus
N103 N-Glycosylation GlyGen   UniProt 16335952, 19159218, 21768352, ...24190977, 23090970, 29391424, 19139490, 19838169, 23345538, 29741879, 29671580, 30237853
N177 N-Glycosylation GlyGen   UniProt 16335952, 32125861, 21768352, ...23090970, 29391424, 29741879, 29671580
Y206 Phosphorylation PhosphoSitePlus
T425 Phosphorylation PhosphoSitePlus
N464 N-Glycosylation GlyGen   UniProt 16335952, 34725484, 21768352, ...23090970, 14760718, 29391424, 29741879, 29671580
S483 Phosphorylation PhosphoSitePlus
N494 N-Glycosylation GlyGen   UniProt 29741879, 29671580, 21768352, ...29391424, 23345538
N536 N-Glycosylation GlyGen   UniProt 16335952, 29741879, 21768352
Site PTM Type PTM Enzyme Score Source PMID
N103 N-Glycosylation PRO 19838169, 29671580, 23345538
N177 N-Glycosylation PRO 29671580
N464 N-Glycosylation PRO 29671580
N494 N-Glycosylation PRO 29671580, 23345538


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y22 H22 Biomuta DOID:4159 / skin cancer [ cosmic ]
N70 I70 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S483 L483 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic ]