Protein Information

Cytoscape View

UniProt AC / UniProt ID P05154 / IPSP_HUMAN
Protein Name Plasma serine protease inhibitor precursor
Gene Name Name: SERPINA5
Organism Homo sapiens (Human)

PRO ID PR:P05154
DAG View
PRO Name plasma serine protease inhibitor (human)
Definition A plasma serine protease inhibitor that is encoded in the genome of human.
Short Label hSERPINA5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P05154 (SERPINA5) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S13 Phosphorylation PhosphoSitePlus
S18 Phosphorylation PhosphoSitePlus
T39 O-Glycosylation PhosphoSitePlus   UniProt 21056543, 22171320
T218 Phosphorylation PhosphoSitePlus
N249 N-Glycosylation UniProt 14760718, 18467335
N262 N-Glycosylation UniProt 16335952, 12575940, 18467335
N338 N-Glycosylation UniProt 16335952, 18467335

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T39 M39 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:9256 / colorectal cancer [ icgc ] DOID:10534 / stomach cancer [ tcga ]
T218 A218 Biomuta DOID:1115 / sarcoma [ tcga ]
T218 I218 Biomuta DOID:10283 / prostate cancer [ cosmic ]
N262 D262 Biomuta DOID:10534 / stomach cancer [ cosmic ]
N338 D338 Biomuta DOID:1324 / lung cancer [ cosmic ]