iPTMnet Report for P05154 (SERPINA5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P05154 / IPSP_HUMAN
Protein Name Plasma serine protease inhibitor precursor
Gene Name Name: SERPINA5
Synonyms:PCI,PLANH3,PROCI;
Organism Homo sapiens (Human)

PRO ID PR:P05154
DAG View
PRO Name plasma serine protease inhibitor (human)
Definition A plasma serine protease inhibitor that is encoded in the genome of human.
Short Label hSERPINA5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P05154 (SERPINA5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S13 Phosphorylation PhosphoSitePlus
S18 Phosphorylation PhosphoSitePlus
T39 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 23584533, 21056543, 22171320
T218 Phosphorylation PhosphoSitePlus
N249 N-Glycosylation GlyGen   UniProt 23090970, 24190977, 14760718, ...18467335
N262 N-Glycosylation GlyGen   UniProt 16335952, 30237853, 24190977, ...23090970, 26791533, 29391424, 29741879, 12575940, 29671580, 18467335
N338 N-Glycosylation GlyGen   UniProt 16335952, 23090970, 18467335
Site PTM Type PTM Enzyme Score Source PMID
N262 N-Glycosylation PRO 26791533, 29671580


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S18 F18 Biomuta DOID:4159 / skin cancer [ cosmic ]
T39 M39 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
T218 A218 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
T218 I218 Biomuta DOID:10283 / prostate cancer [ cosmic ]
N262 D262 Biomuta DOID:10534 / stomach cancer [ cosmic ]
N338 D338 Biomuta DOID:1324 / lung cancer [ cosmic ]