Protein Information

Cytoscape View


UniProt AC / UniProt ID P05089 / ARGI1_HUMAN
Protein Name Arginase-1
Gene Name Name: ARG1
Organism Homo sapiens (Human)

PRO ID PR:P05089
DAG View
PRO Name arginase-1 (human)
Definition An arginase-1 that is encoded in the genome of human.
Short Label hARG1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P05089 (ARG1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S16 Phosphorylation PhosphoSitePlus
T29 Phosphorylation PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus
Y50 Phosphorylation PhosphoSitePlus
S62 Phosphorylation PhosphoSitePlus   UniProt 24275569
S72 Phosphorylation PhosphoSitePlus
S94 Phosphorylation PhosphoSitePlus
S102 Phosphorylation PhosphoSitePlus
S107 Phosphorylation PhosphoSitePlus
S109 Phosphorylation PhosphoSitePlus
S163 Phosphorylation PhosphoSitePlus   UniProt 24275569
T166 Phosphorylation PhosphoSitePlus
C168 S-Nitrosylation dbSNO 17704205, 22178444
S170 Phosphorylation PhosphoSitePlus
K191 Acetylation PhosphoSitePlus
S217 Phosphorylation PhosphoSitePlus   UniProt 24275569
Y265 Phosphorylation PhosphoSitePlus
C303 S-Nitrosylation dbSNO 17704205, 22178444
Site PTM Type PTM Enzyme Score Source PMID
S163 Phosphorylation HPRD 20166139
T166 Phosphorylation HPRD 20166139


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S16 * Biomuta DOID:1324 / lung cancer [ icgc, tcga ]
S72 Y72 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ] DOID:10534 / stomach cancer [ tcga ]
S94 R94 Biomuta DOID:363 / uterine cancer [ tcga ]
S109 P109 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
T166 I166 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
C168 F168 Biomuta DOID:3571 / liver cancer [ icgc ]