Protein Information

Cytoscape View


UniProt AC / UniProt ID P05019 / IGF1_HUMAN
Protein Name Insulin-like growth factor I precursor
Gene Name Name: IGF1
Synonyms:IBP1;
Organism Homo sapiens (Human)

PRO ID PR:P05019
DAG View
PRO Name insulin-like growth factor I (human)
Definition An insulin-like growth factor I that is encoded in the genome of human.
Short Label hIGF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P05019 (IGF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T47 Phosphorylation RLIMS-P 26276395
K134 Ubiquitination PhosphoSitePlus
Y135 Phosphorylation PhosphoSitePlus
S184 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y151 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S184 R184 Biomuta DOID:1324 / lung cancer [ cosmic ]
S184 T184 Biomuta DOID:1324 / lung cancer [ cosmic ]