iPTMnet Report for P04920 (SLC4A2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P04920 / B3A2_HUMAN
Protein Name Anion exchange protein 2
Gene Name Name: SLC4A2
Synonyms:AE2,EPB3L1,HKB3,MPB3L;
Organism Homo sapiens (Human)

PRO ID PR:P04920
DAG View
PRO Name anion exchange protein 2 (human)
Definition An anion exchange protein 2 that is encoded in the genome of human.
Short Label hSLC4A2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P04920 (SLC4A2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T27 Phosphorylation PhosphoSitePlus
S56 Phosphorylation PhosphoSitePlus
R57 Methylation PhosphoSitePlus
S65 Phosphorylation PhosphoSitePlus
Y66 Phosphorylation PhosphoSitePlus
Y73 Phosphorylation PhosphoSitePlus
S113 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T115 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T118 Phosphorylation PhosphoSitePlus
S132 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S144 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
T148 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S150 Phosphorylation PhosphoSitePlus
S151 Phosphorylation PhosphoSitePlus
T169 Phosphorylation PhosphoSitePlus
S170 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S172 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S173 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T183 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S232 Phosphorylation PhosphoSitePlus
Y233 Phosphorylation PhosphoSitePlus
S243 Phosphorylation PhosphoSitePlus   UniProt 23186163
T245 Phosphorylation PhosphoSitePlus
T257 Phosphorylation PhosphoSitePlus
T264 Phosphorylation PhosphoSitePlus
K274 Methylation PhosphoSitePlus   UniProt 24129315
T309 Phosphorylation PhosphoSitePlus
K319 Ubiquitination PhosphoSitePlus
K334 Ubiquitination PhosphoSitePlus
K362 Ubiquitination PhosphoSitePlus
K426 Ubiquitination PhosphoSitePlus
K434 Ubiquitination PhosphoSitePlus
S443 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983
S446 Phosphorylation PhosphoSitePlus
S449 Phosphorylation PhosphoSitePlus
S461 Phosphorylation PhosphoSitePlus
S500 Phosphorylation PhosphoSitePlus
K505 Ubiquitination PhosphoSitePlus
K636 Ubiquitination PhosphoSitePlus
K653 Ubiquitination PhosphoSitePlus
K658 Ubiquitination PhosphoSitePlus
N868 N-Glycosylation GlyGen 24190977
N882 N-Glycosylation GlyGen 24190977
K893 Ubiquitination PhosphoSitePlus
K975 Ubiquitination PhosphoSitePlus
K1073 Ubiquitination PhosphoSitePlus
K1080 Ubiquitination PhosphoSitePlus
K1087 Ubiquitination PhosphoSitePlus
Y1154 Phosphorylation PhosphoSitePlus
K1156 Ubiquitination PhosphoSitePlus
Y1234 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S113 Phosphorylation HPRD 18669648, 20068231
T115 Phosphorylation HPRD 18669648
T118 Phosphorylation HPRD 17081983
S132 Phosphorylation HPRD 18669648
S144 Phosphorylation HPRD 18669648, 20068231
T148 Phosphorylation HPRD 18669648
T169 Phosphorylation HPRD 19413330, 17081983, 20068231
S170 Phosphorylation HPRD 18669648, 17081983, 20068231
S172 Phosphorylation HPRD 19413330, 18669648, 20068231, ...18452278
S173 Phosphorylation HPRD 18669648, 17081983, 20068231
T183 Phosphorylation HPRD 18669648
S446 Phosphorylation HPRD 17081983
S449 Phosphorylation HPRD 17081983
S461 Phosphorylation HPRD 17081983, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T27 A27 Biomuta DOID:3277 / thymus cancer [ cosmic ]
T27 M27 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R57 C57 Biomuta DOID:4159 / skin cancer [ cosmic ]
R57 H57 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
Y73 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S144 P144 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T183 S183 Biomuta [ cosmic ]
T257 M257 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S449 F449 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K1087 N1087 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]