iPTMnet Report for P04807 (HXK2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P04807 / HXKB_YEAST
Protein Name Hexokinase-2
Gene Name Name: HXK2
Synonyms:HEX1,HKB;OrderedLocusNames:YGL253W;ORFNames:NRB486;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

PRO ID PR:P04807
DAG View
PRO Name hexokinase-2 (yeast)
Definition A protein that is a translation product of the HXK2 gene in yeast.
Short Label yHXK2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P04807 (HXK2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K7 Sumoylation SGD 33502312
K13 Methylation SGD 27115613
K13 Sumoylation SGD 33502312
S15 Phosphorylation BioGRID   RLIMS-P   SGD   UniProt 9718324, 11875433, 33232441, ...15665377, 21126336, 33491328, 30516470, 33481703, 32597660, 9047292, 36302925, 10428955, 9566913, 22289182, 11170432, 23066030, 23273919, 20702584, 8286332, 21177495, 19779198, 19684113
T35 Phosphorylation SGD 33491328
T38 Phosphorylation BioGRID   SGD   UniProt 33481703, 18407956, 33491328
S50 Phosphorylation BioGRID   SGD 19779198, 33491328
K54 Acetylation SGD 22865919
D72 Methylation SGD 25109467
K98 Acetylation SGD 22865919
T104 Phosphorylation SGD 23749301, 33491328
K111 Acetylation SGD 22865919
K111 Ubiquitination SGD 23749301
S158 Phosphorylation BioGRID   RLIMS-P   SGD   UniProt 9047292, 33232441, 33491328, ...18407956
T175 Phosphorylation SGD 33491328
K194 Acetylation SGD 22865919
S245 Phosphorylation BioGRID   SGD   UniProt 19779198, 33491328, 18407956
S272 Phosphorylation SGD 33491328, 18407956
K284 Acetylation SGD 22865919
S293 Phosphorylation SGD 32597660, 23749301, 33491328
S305 Phosphorylation SGD 33481703
S306 Phosphorylation SGD 33481703
K329 Acetylation SGD 22865919
K335 Acetylation SGD 22865919
K338 Acetylation SGD 22865919
K338 Ubiquitination SGD 23749301
S385 Phosphorylation SGD 33481703, 33491328, 23749301
S396 Phosphorylation BioGRID 17287358
K406 Ubiquitination SGD 23749301
K410 Acetylation SGD 22865919
K410 Sumoylation SGD 33502312
S419 Phosphorylation BioGRID   SGD 19779198, 32597660, 33481703, ...18407956, 33491328
Y424 Phosphorylation SGD 33491328
K430 Ubiquitination SGD 23749301
D437 Methylation SGD 27115613
W441 Methylation SGD 27115613
T442 Phosphorylation SGD 33491328
D448 Methylation SGD 27115613
S460 Phosphorylation SGD 33481703, 33491328