iPTMnet Report for P04798 (CYP1A1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P04798 / CP1A1_HUMAN
Protein Name Cytochrome P450 1A1
Gene Name Name: CYP1A1
Organism Homo sapiens (Human)

PRO ID PR:P04798
DAG View
PRO Name cytochrome P450 1A1 (human)
Definition A cytochrome P450 1A1 that is encoded in the genome of human.
Short Label hCYP1A1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P04798 (CYP1A1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S247 Phosphorylation PhosphoSitePlus
Y270 Phosphorylation PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
S360 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
Site PTM Type PTM Enzyme Score Source PMID
S360 Phosphorylation HPRD 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S247 P247 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y270 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K271 T271 Biomuta DOID:363 / uterine cancer [ icgc ]
S360 F360 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ]