iPTMnet Report for P04786 (TOP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P04786 / TOP1_YEAST
Protein Name DNA topoisomerase 1
Gene Name Name: TOP1
Synonyms:MAK1;OrderedLocusNames:YOL006C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

PRO ID PR:P04786
DAG View
PRO Name DNA topoisomerase 1 (yeast)
Definition A protein that is a translation product of the TOP1 gene in yeast.
Short Label yTOP1
Category organism-gene

Interactive Sequence View

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P04786 (TOP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S14 Phosphorylation BioGRID   SGD   UniProt 19795423, 19823750, 17563356, ...17330950, 20702584, 18407956, 23749301, 19779198, 30516470, 19684113, 21177495, 33491328, 33481703
S15 Phosphorylation BioGRID   SGD   UniProt 19795423, 19823750, 17563356, ...17330950, 20702584, 18407956, 23749301, 19779198, 30516470, 19684113, 21177495, 33491328, 33481703
S24 Phosphorylation SGD   UniProt 33481703, 30516470, 33491328, ...18407956, 23749301
T26 Phosphorylation BioGRID   SGD 30516470, 19795423, 19823750, ...33481703
S34 Phosphorylation BioGRID 21126336
S39 Phosphorylation SGD 23749301, 33481703
Y47 Phosphorylation BioGRID   SGD 19795423, 33481703, 17330950, ...20702584, 19779198, 21725298, 19823750
S49 Phosphorylation BioGRID   SGD   UniProt 19795423, 19823750, 17563356, ...17330950, 20702584, 18407956, 23749301, 22218487, 19779198, 30516470, 32597660, 33491328, 33481703
S54 Phosphorylation BioGRID   SGD 33481703, 18407956
T66 Phosphorylation BioGRID   SGD 21126336, 33481703
S71 Phosphorylation SGD 32597660, 33481703
S72 Phosphorylation SGD 33481703
S73 Phosphorylation SGD 33481703
S76 Phosphorylation BioGRID   SGD   UniProt 33481703, 17330950, 32597660, ...18407956, 33491328, 19779198, 21177495, 23749301
K91 Sumoylation SGD 33502312
K125 Sumoylation SGD 33502312
S355 Phosphorylation SGD 33491328
S426 Phosphorylation SGD 23749301, 33491328
S437 Phosphorylation SGD 33491328
K535 Sumoylation SGD 33502312
K596 Sumoylation SGD 33502312
K644 Sumoylation SGD 33502312
K647 Sumoylation SGD 33502312
K657 Sumoylation SGD 33502312
K675 Sumoylation SGD 33502312
S706 Phosphorylation SGD 33491328
S716 Phosphorylation SGD 33491328