Protein Information

Cytoscape View


UniProt AC / UniProt ID P04746 / AMYP_HUMAN
Protein Name Pancreatic alpha-amylase precursor
Gene Name Name: AMY2A
Organism Homo sapiens (Human)

PRO ID PR:P04746
DAG View
PRO Name pancreatic alpha-amylase (human)
Definition An alpha-amylase 2A that is encoded in the genome of human.
Short Label hAMY2A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P04746 (AMY2A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y67 Phosphorylation PhosphoSitePlus
Y77 Phosphorylation PhosphoSitePlus
S81 Phosphorylation PhosphoSitePlus
Y82 Phosphorylation PhosphoSitePlus
Y166 Phosphorylation PhosphoSitePlus
Y189 Phosphorylation PhosphoSitePlus
Y197 Phosphorylation PhosphoSitePlus
Y273 Phosphorylation PhosphoSitePlus
N476 N-Glycosylation UniProt 10091666, 11772019, 10769135


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y67 H67 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
Y77 * Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
Y273 C273 Biomuta DOID:1612 / breast cancer [ tcga ]