iPTMnet Report for P04424 (ASL)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P04424 / ARLY_HUMAN
Protein Name Argininosuccinate lyase
Gene Name Name: ASL
Organism Homo sapiens (Human)

PRO ID PR:P04424
DAG View
PRO Name argininosuccinate lyase (human)
Definition An argininosuccinate lyase that is encoded in the genome of human.
Short Label hASL
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P04424 (ASL) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S5 Phosphorylation PhosphoSitePlus
K7 Ubiquitination PhosphoSitePlus
K23 Ubiquitination PhosphoSitePlus
K43 Ubiquitination PhosphoSitePlus
K51 Ubiquitination PhosphoSitePlus
K57 Ubiquitination PhosphoSitePlus
K69 Acetylation PhosphoSitePlus   UniProt 20167786
K80 Ubiquitination PhosphoSitePlus
S83 Phosphorylation PhosphoSitePlus
T90 Phosphorylation PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
T103 Phosphorylation PhosphoSitePlus
K106 Methylation PhosphoSitePlus
K106 Ubiquitination PhosphoSitePlus
K287 Ubiquitination PhosphoSitePlus
K288 Acetylation PhosphoSitePlus   UniProt 20167786
K288 Ubiquitination PhosphoSitePlus
K323 Ubiquitination PhosphoSitePlus
Y376 Phosphorylation PhosphoSitePlus
S417 Phosphorylation PhosphoSitePlus
S446 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T103 M103 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]