iPTMnet Report P04234 CD3D

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P04234 / CD3D_HUMAN
Protein Name	T-cell surface glycoprotein CD3 delta chain precursor
Gene Name	Name: CD3D Synonyms:T3D;
Organism	Homo sapiens (Human)

PRO ID	PR:P04234 DAG View
PRO Name	T-cell surface glycoprotein CD3 delta chain (human)
Definition	A CD3 delta that is encoded in the genome of human.
Short Label	hCD3D
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P04234 (CD3D) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	K62	Ubiquitination		score1	PhosphoSitePlus
	K80	Ubiquitination		score1	PhosphoSitePlus
	K82	Ubiquitination		score1	PhosphoSitePlus
	T139	Phosphorylation		score1	PhosphoSitePlus
	Y149	Phosphorylation		score2	phospho.ELM PRO PhosphoSitePlus UniProt	15659558, 16094384, 15144186, ...15592455, 12522270
	Y160	Phosphorylation		score2	phospho.ELM PRO PhosphoSitePlus UniProt	15659558, 16094384, 15592455, ...12522270, 19690332
	S161	Phosphorylation		score1	PhosphoSitePlus

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	Y149	Phosphorylation		score0	HPRD	12522270, 15144186
	Y160	Phosphorylation		score0	HPRD	12522270

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	Y105	Phosphorylation		score0	HPRD	15592455
	Y116	Phosphorylation		score0	HPRD	15592455

Proteoforms

	PRO ID (Short Label)	Sites	PTM Enzyme	Source	PMID
	PR:000046638 (hCD3D/SigPep-/Phos:1)	pY149,pY160		PRO

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
K62	E62	Biomuta		DOID:3571 / liver cancer [ cosmic ]