iPTMnet Report for P04196 (HRG)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P04196 / HRG_HUMAN
Protein Name Histidine-rich glycoprotein precursor
Gene Name Name: HRG
Organism Homo sapiens (Human)

PRO ID PR:P04196
DAG View
PRO Name histidine-rich glycoprotein (human)
Definition A histidine-rich glycoprotein that is encoded in the genome of human.
Short Label hHRG
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P04196 (HRG) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y46 Phosphorylation PhosphoSitePlus
N63 N-Glycosylation GlyGen   UniProt 16335952, 19285951, 23090970, ...29741879
Y67 Phosphorylation PhosphoSitePlus
Y68 Phosphorylation PhosphoSitePlus
N125 N-Glycosylation GlyGen   UniProt 16335952, 24530628, 19159218, ...23090970, 29391424, 24279413, 29741879, 29671580
T128 Phosphorylation PhosphoSitePlus
Y165 Phosphorylation PhosphoSitePlus
S174 Phosphorylation PhosphoSitePlus
S271 O-Glycosylation GlyGen 30459171
T273 O-Glycosylation GlyGen 30459171
T274 O-Glycosylation GlyGen 30459171
S283 Phosphorylation PhosphoSitePlus
N344 N-Glycosylation GlyGen   UniProt 16335952, 23090970, 29391424, ...29741879
Site PTM Type PTM Enzyme Score Source PMID
N125 N-Glycosylation PRO 24279413, 29671580


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y46 F46 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S174 F174 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S271 Y271 Biomuta DOID:9256 / colorectal cancer [ cosmic ]