iPTMnet Report for P04181 (OAT)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P04181 / OAT_HUMAN
Protein Name Ornithine aminotransferase, mitochondrial precursor
Gene Name Name: OAT
Organism Homo sapiens (Human)

PRO ID PR:P04181
DAG View
PRO Name ornithine aminotransferase, mitochondrial (human)
Definition An ornithine aminotransferase, mitochondrial that is encoded in the genome of human.
Short Label hOAT
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P04181 (OAT) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T30 Phosphorylation PhosphoSitePlus
K32 Ubiquitination PhosphoSitePlus
T39 Phosphorylation PhosphoSitePlus
K49 Ubiquitination PhosphoSitePlus
Y55 Phosphorylation PhosphoSitePlus
K66 Ubiquitination PhosphoSitePlus
Y69 Phosphorylation PhosphoSitePlus
K77 Acetylation PhosphoSitePlus
Y85 Phosphorylation PhosphoSitePlus
K96 Acetylation PhosphoSitePlus
K102 Ubiquitination PhosphoSitePlus
Y123 Phosphorylation PhosphoSitePlus
Y126 Phosphorylation PhosphoSitePlus
Y133 Phosphorylation PhosphoSitePlus
K151 Ubiquitination PhosphoSitePlus
T272 Phosphorylation PhosphoSitePlus
Y280 Phosphorylation PhosphoSitePlus
C306 S-Nitrosylation dbSNO 26338901
C330 S-Nitrosylation dbSNO 26338901
K362 Ubiquitination PhosphoSitePlus
S365 Phosphorylation PhosphoSitePlus
K374 Ubiquitination PhosphoSitePlus
K386 Ubiquitination PhosphoSitePlus
K392 Ubiquitination PhosphoSitePlus
K405 Ubiquitination PhosphoSitePlus
R426 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T272 Phosphorylation HPRD 20068231
T369 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K49 N49 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K66 N66 Biomuta DOID:363 / uterine cancer [ icgc ]
K96 N96 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K102 N102 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y133 H133 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
Y280 H280 Biomuta DOID:3571 / liver cancer [ cosmic ]
C330 Y330 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T369 I369 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R426 Q426 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]