iPTMnet Report P04180 LCAT

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P04180 / LCAT_HUMAN
Protein Name	Phosphatidylcholine-sterol acyltransferase precursor
Gene Name	Name: LCAT
Organism	Homo sapiens (Human)

PRO ID	PR:P04180 DAG View
PRO Name	phosphatidylcholine-sterol acyltransferase (human)
Definition	A phosphatidylcholine-sterol acyltransferase that is encoded in the genome of human.
Short Label	hLCAT
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P04180 (LCAT) as Substrate

P04180

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	N44	N-Glycosylation		score4	GlyGen UniProt	16335952, 7613477, 23090970, ...29391424, 24190977
	N108	N-Glycosylation		score4	GlyGen UniProt	26195816, 7613477
	S205	Phosphorylation		score3	phospho.ELM PhosphoSitePlus	3128170
	Y213	Phosphorylation		score1	PhosphoSitePlus
	N296	N-Glycosylation		score4	GlyGen UniProt	16335952, 23090970, 7613477, ...26195816, 29391424
	S376	Phosphorylation		score1	PhosphoSitePlus
	T377	Phosphorylation		score1	PhosphoSitePlus
	N408	N-Glycosylation		score4	GlyGen UniProt	26195816, 7613477
	T431	O-Glycosylation		score3	GlyGen UniProt	7613477
	S433	O-Glycosylation		score3	GlyGen UniProt	7613477

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
S376	I376	Biomuta		DOID:9256 / colorectal cancer [ cosmic, icgc ]