Protein Information

Cytoscape View

UniProt AC / UniProt ID P04180 / LCAT_HUMAN
Protein Name Phosphatidylcholine-sterol acyltransferase precursor
Gene Name Name: LCAT
Organism Homo sapiens (Human)

PRO ID PR:P04180
DAG View
PRO Name phosphatidylcholine-sterol acyltransferase (human)
Definition A phosphatidylcholine-sterol acyltransferase that is encoded in the genome of human.
Short Label hLCAT
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P04180 (LCAT) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
N44 N-Glycosylation UniProt 16335952, 7613477
N108 N-Glycosylation UniProt 26195816, 7613477
S205 Phosphorylation phospho.ELM   PhosphoSitePlus 3128170
Y213 Phosphorylation PhosphoSitePlus
N296 N-Glycosylation UniProt 16335952, 26195816, 7613477
S376 Phosphorylation PhosphoSitePlus
T377 Phosphorylation PhosphoSitePlus
N408 N-Glycosylation UniProt 26195816, 7613477
T431 O-Glycosylation UniProt 7613477
S433 O-Glycosylation UniProt 7613477

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S376 I376 Biomuta DOID:9256 / colorectal cancer [ tcga ]