iPTMnet Report for P04179 (SOD2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P04179 / SODM_HUMAN
Protein Name Superoxide dismutase [Mn], mitochondrial precursor
Gene Name Name: SOD2
Organism Homo sapiens (Human)

PRO ID PR:P04179
DAG View
PRO Name superoxide dismutase [Mn], mitochondrial (human)
Definition A superoxide dismutase [Mn], mitochondrial that is encoded in the genome of human.
Short Label hSOD2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P04179 (SOD2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K53 Acetylation PhosphoSitePlus
Y58 Phosphorylation PhosphoSitePlus
K68 Acetylation PhosphoSitePlus   UniProt 19608861
T79 Phosphorylation PhosphoSitePlus
S106 Phosphorylation PhosphoSitePlus   RLIMS-P 23243068, 25578653
S106 Phosphorylation P06493 (CDK1) PhosphoSitePlus 23243068
S106 Phosphorylation P11802 (CDK4) PhosphoSitePlus 25578653
K122 Acetylation PhosphoSitePlus
K122 Methylation PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
S127 Phosphorylation PhosphoSitePlus
K130 Acetylation PhosphoSitePlus   UniProt 19608861
K130 Methylation PhosphoSitePlus
K130 Ubiquitination PhosphoSitePlus
K132 Acetylation PhosphoSitePlus
R197 Methylation PhosphoSitePlus
K221 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S127 F127 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]